Results 71 to 80 of about 50,999 (231)
Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins
Developmental Dynamics, EarlyView.Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming +14 more
wiley +1 more source
A pictorial review of traumatic pericardial injuries
Insights into Imaging, 2012 Background Thoracic injuries are the third most common injuries in trauma patients with cardiac injuries amongst the most lethal. Imaging is essential in diagnosis and triage of patients with pericardial injuries, and this review aims to highlight the ...
Ashok Adams +4 more
doaj +1 more source
Developmental Dynamics, EarlyView.Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez +4 more
wiley +1 more source
Streptozotocin induced hyperglycemia in the axolotl
Developmental Dynamics, EarlyView.Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen +2 more
wiley +1 more source
Pericardial effusion in oncological patients: current knowledge and principles of management
Cardio-OncologyBackground This article provides an up-to-date overview of pericardial effusion in oncological practice and a guidance on its management. Furthermore, it addresses the question of when malignancy should be suspected in case of newly diagnosed pericardial
S. Mori +7 more
doaj +1 more source
Biomarkers of lung congestion and injury in acute heart failure
ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi +9 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer +25 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Stillbirths affect millions of pregnancies every year worldwide, and obstruction of the umbilical cord blood flow is one of the main causes of fetal death. This review provides a clinico‐pathological overview of cord abnormalities potentially associated with antepartum stillbirth, describing the mechanism determining the death and addressing ...
Laura Avagliano +3 more
wiley +1 more source
Echocardiographic Evaluation of Pericardial Effusion and Cardiac Tamponade
Frontiers in Pediatrics, 2017 Pericardial effusion (PEff) is defined by an increase in the physiological amount of fluid within the pericardial space. It can appear following different medical conditions, mainly related to inflammation and cardiac surgery.
Joan Sanchez-de-Toledo +4 more
doaj +1 more source