Results 71 to 80 of about 45,973 (216)

Risk Factors for Cutaneous Immune‐Related Adverse Events in the Japanese Population: A Retrospective Single‐Center Cohort Study

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe   +4 more
wiley   +1 more source

The Use of IL-1 Receptor Antagonist (Anakinra) in Idiopathic Recurrent Pericarditis: A Narrative Review

open access: yesCardiology Research and Practice, 2016
Recurrent pericarditis is a complication of acute pericarditis in 20–30% of the patients and is usually idiopathic in nature. The underlying pathogenesis of this condition remains unclear, although immune-mediated mechanisms seem likely.
Shankar Baskar   +2 more
doaj   +1 more source

Surgical management of a penetrating cardiac foreign body causing tamponade in a dog: case report

open access: yesAustralian Veterinary Journal, EarlyView.
Background Penetrating cardiac foreign bodies are rare in dogs but can result in life‐threatening complications, including pericardial effusion and cardiac tamponade. Prompt diagnosis, emergency stabilization, and definitive surgical management are essential to achieve a favorable outcome.
RB Abibe   +5 more
wiley   +1 more source

ETIOLOGY OF PERICARDITIS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1884
[Read in the Section of Practice of Medicine and Materia Medica of the American Medical Association. May, 1884.] Pericarditis is a disease of greater frequency than is generally believed. The statement made by the author of this paper in the Cincinnati Academy of Medicine that pericarditis is ordinarily oftener overlooked than recognized, having been ...
openaire   +1 more source

INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol

open access: yesBJU International, EarlyView.
Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan   +13 more
wiley   +1 more source

MORPHOLOGICAL FEATURES OF CONSTRICTIVE PERICARDITIS

open access: yesРоссийский кардиологический журнал, 2010
The features of pericardial morphology in constrictive pericarditis are described, based on the surgery material, which was obtained from 27 patients aged 5-77 years during pericardectomy.
V. V. Kochmasheva   +2 more
doaj  

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Delayed Diagnosis of Constrictive Pericarditis Resulting in Recurrent Heart Failure: A Case Report

open access: yesClinical Medicine Insights: Case Reports
Constrictive pericarditis can lead to compromised diastolic ventricular filling due to pericardial inflammation and fibrosis. A diagnosis of constrictive pericarditis was established by identifying structural and hemodynamic features through ...
Chunliang Wang   +5 more
doaj   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam   +3 more
wiley   +1 more source

Purulent Pericarditis in an Immunocompetent Young Child

open access: yesJournal of Pediatric Research
Purulent pericarditis in children is a life-threatening condition causing cardiac tamponade and disrupting the hemodynamic status of the patient. It has been associated with high mortality if treatment is delayed.
Şeyma Şebnem Ön   +9 more
doaj   +1 more source

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