Results 101 to 110 of about 109,588 (359)

Pulmonary Valve Replacement Using an Intraoperatively Created Trileaflet Autologous Pericardial Valve: A Case Series [PDF]

Iranian Journal of Medical Sciences
Background: Pulmonary valve replacement is inevitable for the majority of patients with long-standing pulmonary regurgitation. The purpose of this study was to describe the experience of employing a novel technique to create an intraoperatively handmade ...
Ahmad Ali Amirghofran, Kamran Jamshidi, Mohammadreza Edraki, Gholamhossein Ajami, Hamid Amoozgar, Mohammadreza Sabri, Hamid Arabi, Elahe Nirooie, Mohammad Kasaie, Rahim Hemmati, Mina Amiri   +10 more
doaj   +1 more source

Epidermal Interferon‐κ Drives Cutaneous Lupus‐Like Lesions, Photosensitivity, and Systemic Autoimmunity In Vivo

Arthritis &Rheumatology, EarlyView.
Objective Keratinocyte‐derived interferon (IFN) κ is chronically overexpressed in human nonlesional systemic lupus erythematosus (SLE) skin. Recent evidence suggests that epidermal signals instruct the immune system in SLE, but whether epidermal IFNκ alone is sufficient to drive lupus phenotypes has not been investigated.
Benjamin Klein, Deborah J. Colesa, Yiqing Gao, Patrick A. O'Brien, Lin Zhang, Lori Lowe, Kelsey E. McNeely, Nguyen Thi Kim Nguyen, Svenja Henning, Mehrnaz Gharaee‐Kermani, Jeffrey B. Hodgin, Jacob W. S. Martens, Johann E. Gudjonsson, Celine C. Berthier, J. Michelle Kahlenberg   +14 more
wiley   +1 more source

The effects of cross linking on collagen type 1 nanostructure and nanostructural response to uniaxial tension : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Engineering at Massey University, Manawatu, New Zealand [PDF]

, 2016
Reproduced by permission of The Royal Society of Chemistry: Kayed, H. R., Sizeland, K. H., Kirby, N., Hawley, A., Mudie, S. T., & Haverkamp, R. G. (2015). Collagen cross linking and fibril alignment in pericardium. RSC Advances, 5, 3611-3618.
Kayed, Hanan
core  

Comparative Analysis of Cannabidiol and Risperidone on Behavioral and Neurochemical Outcomes, and Neurodevelopment Markers in a Zebrafish Model of Embryonic Exposure to Sodium Valproate

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social communication deficits, repetitive behaviors, and sensory abnormalities. Sodium valproate (VPA) exposure during embryonic development is a well‐established preclinical model for ASD, leading to increased oxidative stress in the developing brain, including ...
Karla C. M. Costa, Tamires A. V. Brigante, Pedro H. C. Lirio, Gabriel G. Fernandes, Franciele F. Scarante, Davi S. Scomparin, Rafael R. Ferreira, Maria A. Vicente, Flavia R. Abe, Francisco S. Guimarães, Jaime E. C. Hallak, Jose A. Crippa, Danielle P. de Oliveira, Alline C. Campos   +13 more
wiley   +1 more source

Oligosaccharide Lactate Nanoparticles Enhance Tissue Targeting: A Case Study of the Controlled Delivery of Bedaquiline to Cardiac Tissue in TB Pericarditis

Molecules
Bedaquiline is known to shorten the duration of therapy of tuberculosis but has limitations, e.g., poor solubility and adverse effects such as prolongation of the QT interval.
Simisola Ayodele, Pradeep Kumar, Armorel van Eyk, Pieter van der Bijl, Yahya E. Choonara   +4 more
doaj   +1 more source

Transapical off-pump mitral valve repair with Neochord Implantation (TOP-MINI): step-by-step guide [PDF]

, 2015
open10openColli, Andrea; Zucchetta, Fabio; Torregrossa, Gianluca; Manzan, Erica; Bizzotto, Eleonora; Besola, Laura; Bellu, Roberto; Sarais, Cristiano; Pittarello, Demetrio; Gerosa, GinoColli, Andrea; Zucchetta, Fabio; Torregrossa, Gianluca; Manzan, Erica;
Bellu, Roberto, Besola, Laura, Bizzotto, Eleonora, Colli, Andrea, Gerosa, Gino, Manzan, Erica, Pittarello, Demetrio, Sarais, Cristiano, Torregrossa, Gianluca, Zucchetta, Fabio   +9 more
core   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Parâmetros ecocardiográficos de deposição de gordura epicárdica e sua relação com doença arterial coronariana Parámetros ecocardiográficos de deposición de grasa epicárdica y su relación con la enfermedad arterial coronaria Echocardiographic parameters of epicardial fat deposition and its relation to coronary artery disease

Arquivos Brasileiros de Cardiologia, 2011
FUNDAMENTO: Gordura epicárdica tem sido associada com a presença de doença arterial coronariana (DAC) significante. Entretanto, a associação entre infiltração lipomatosa do septo atrial e a infiltração de gordura do ventrículo direito (VD) permanece ...
Juan Valiente Mustelier, Julio Oscar Cabrera Rego, Angela Gala González, Júlio César Gandarilla Sarmiento, Beatriz Vega Riverón   +4 more
doaj  

Adipocytes in Aortic Stenosis: Association With Clinical and Morphological Indices

Clinical Anatomy, EarlyView.
ABSTRACT Recently, great attention has been given to understanding the new pathogenetic mechanisms underlying aortic stenosis (AS). The study aims to understand the role of mature adipocytes in AS and their association with histologic, clinical, and echocardiographic data, an area previously overlooked in AS research.
Elena Zoico, Tanaz Saatchi, Silvia Urbani, Vanni Rizzatti, Gloria Mazzali, Francesco Fantin, Silvia Faccioli, Alessandro Gavras, Mauro Zamboni, Anna Giani   +9 more
wiley   +1 more source

Building Disease Detection Algorithms with Very Small Numbers of Positive Samples

, 2018
Although deep learning can provide promising results in medical image analysis, the lack of very large annotated datasets confines its full potential.
DJ Penny, HC Shin, L Fei-Fei, O Ronneberger, SM O’Leary, T Geva   +5 more
core   +1 more source