Results 161 to 170 of about 102,619 (391)

Analysis of chronic rejection and obliterative arteriopathy: Possible contributions of donor antigen-presenting cells and lymphatic disruption [PDF]

open access: yes, 1997
Sequential analysis of changes that lead to chronic rejection was undertaken in an animal model of chronic rejection and obliterative arteriopathy. Brown Norway rats are pretreated with a Lewis bone marrow infusion or a Lewis orthotopic liver allograft ...
Demetris, AJ   +10 more
core   +1 more source

A Case Series and Literature Review of Angiosarcoma With Malignant Effusion—A Challenging Cytologic Diagnosis With Dire Prognostic Implications

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Angiosarcoma with malignant effusion is an uncommon yet clinically aggressive presentation, which poses as a diagnostic pitfall with its overlapping cytomorphologic features with metastatic adenocarcinoma. In this article, two cases reported in the literature were reviewed for cytology, immunocytochemistry, and clinical course.
Jamie C. Y. Lam   +3 more
wiley   +1 more source

Surgical resection combined with perioperative chemotherapy for a patient with locally recurrent, previously stage IV thymic small‐cell carcinoma: A case report

open access: yesThoracic Cancer, Volume 13, Issue 23, Page 3415-3419, December 2022., 2022
We present the case of an elderly man with thymic small‐cell carcinoma, a thymic neuroendocrine tumor, where multidisciplinary treatment, including chemotherapy comprising carboplatin and etoposide, and salvage surgery, was considered effective. Chest computed tomography scans show that 4 months after initiation of chemotherapy, the tumor and pleural ...
Junki Terada   +10 more
wiley   +1 more source

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming   +14 more
wiley   +1 more source

Prognostic factors and genetic markers in thymic epithelial tumors: A narrative review

open access: yesThoracic Cancer, Volume 13, Issue 23, Page 3242-3249, December 2022., 2022
The aim of this review article is to discuss the different prognostic factors and genetic markers of TET and to point out discrepancies and similarities among the available literature (concerning prognostic factors) and more importantly to demonstrate the genetic pathways that could be the basis of a development of new targeted therapies.
Apostolos C. Agrafiotis   +5 more
wiley   +1 more source

World of Forms: Deformable Geometric Templates for One-Shot Surface Meshing in Coronary CT Angiography [PDF]

open access: yesarXiv
Deep learning-based medical image segmentation and surface mesh generation typically involve a sequential pipeline from image to segmentation to meshes, often requiring large training datasets while making limited use of prior geometric knowledge. This may lead to topological inconsistencies and suboptimal performance in low-data regimes.
arxiv  

Premature Mortality in Patients With Anorexia Nervosa: A Matched Cohort Study of Cause of Death

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To determine the extent to which anorexia nervosa is associated with premature mortality. Method We carried out a matched cohort study of 7332 male and female patients with anorexia nervosa and 73,215 patient controls who were admitted between 1989 and 2023 in hospital centers of Quebec, Canada. We tracked the patients longitudinally
Nathalie Auger   +7 more
wiley   +1 more source

Phase II study of durvalumab (MEDI 4736) plus carboplatin and etoposide in elderly patients with extensive stage small cell lung cancer: Study protocol of turtle study (LOGIK 2003)

open access: yesThoracic Cancer, Volume 14, Issue 1, Page 105-107, January 2023., 2023
Recently, the addition of anti‐programmed cell death‐ligand 1 (PD‐L1) monoclonal antibodies, including durvalumab and atezolizumab to platinum‐based chemotherapy, has demonstrated clinical benefits in patients with untreated advanced small cell lung cancer (SCLC). However, these clinical trials comprised small populations of elderly patients with SCLC.
Hidenobu Ishii   +8 more
wiley   +1 more source

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