Results 261 to 270 of about 31,673 (300)
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
British Journal of Pharmacology, EarlyView.Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
wiley +1 more source
Cell Proliferation, EarlyView.Elevated COMMD1 contributes to copper efflux in cardiomyocytes during chronic ischaemia in rhesus monkey hearts, regulated by XIAP through post‐translational modification. Our findings suggest a positive feedback loop among XIAP, COMMD1 and copper efflux, contributing to ischaemic cardiomyocyte loss.
Chen Li +10 more
wiley +1 more source
Inflammation in atherosclerotic cardiovascular disease: From diagnosis to treatment
European Journal of Clinical Investigation, EarlyView.Inflammation in atherosclerotic cardiovascular disease. Residual inflammatory risk (RIR), defined by high‐sensitive C‐reactive protein (hsCRP) concentration of ≥2 mg/L, represents a strong predictor of future atherosclerotic cardiovascular disease (ASCVD) events. Although increased hsCRP values ≥2 mg/L might be detected in every three out of five ASCVD
Natalie Arnold, Wolfgang Koenig
wiley +1 more source
European Journal of Clinical Investigation, EarlyView.In a study of 101 idiopathic interstitial pneumonia (IIP) and interstitial pneumonia with autoimmune features (IPAF) patients, 21 (20.8%) were ANCA‐positive. ANCA+ patients had higher rates of NSIP, bronchiectasis, arthralgias, and elevated CRP, with 43% of p‐ANCA+ patients progressing to systemic vasculitis (SV) within 12 months (OR 26.3, p < .0001 ...
Claudia Iannone +11 more
wiley +1 more source
Calcification of implanted xenograft pericardium. Influence of site and function.
, 1984 Shlomo Gabbay +4 more
openalex
Ectopic thyroid carcinoma in the left atrium in a horse
Equine Veterinary Education, EarlyView.Summary A 25‐year‐old Irish sport horse was presented for investigation of a 7‐day history of apathy and lethargy. Clinical examination revealed tachycardia, tachypnoea, distended, pulsating jugular veins and ventral oedema. Serum biochemistry showed azotaemia.
N. Wolf +4 more
wiley +1 more source
Obesity, white adipose tissue and cancer
The FEBS Journal, EarlyView.White adipose tissue (WAT) is essential for energy balance and hormone regulation. In obesity, WAT becomes dysfunctional, leading to inflammation and other changes that promote different stages of carcinogenesis. This review explores how unhealthy WAT under obese conditions supports carcinoma growth through both systemic effects and modulation of the ...
Estel Solsona‐Vilarrasa +1 more
wiley +1 more source
Health and wholeness: a Chinese cultural perspective [PDF]
, 1991 Chong, Yuk Kiong
core +1 more source
Comparative Analysis of Cardiac Catheterisations with Complications (HRG E13) & Cardiac Catheterisations without Complications (HRG E14) [PDF]
, 2000 Cook, Adam, O'Neill, Declan
core