Results 71 to 80 of about 3,531 (197)

Added Value of CCTA-Derived Features to Predict MACEs in Stable Patients Undergoing Coronary Computed Tomography

Diagnostics, 2022
Clinical evidence has emphasized the importance of coronary plaques’ characteristics, rather than lumen stenosis, for the outcome of cardiovascular events.
Valeria Pergola, Giulio Cabrelle, Giulia Mattesi, Simone Cattarin, Antonio Furlan, Carlo Maria Dellino, Saverio Continisio, Carolina Montonati, Adelaide Giorgino, Chiara Giraudo, Loira Leoni, Riccardo Bariani, Giulio Barbiero, Barbara Bauce, Donato Mele, Martina Perazzolo Marra, Giorgio De Conti, Sabino Iliceto, Raffaella Motta   +18 more
doaj   +1 more source

Heart matters: How glucose‐ and lipid‐modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 878-894, February 2026.
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck, Charnkamal Singh Bhogal, Markus Mandl   +2 more
wiley   +1 more source

Towards pericoronary adipose tissue as a clinical imaging marker for coronary inflammation [PDF]

Early detection and treatment of coronary atherosclerosis is essential in reducing the impact of coronary artery disease (CAD). Inflammation plays an important role in the development of coronary atherosclerosis, often preceding plaque formation ...
Ma, Runlei
core   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

High‐intensity statin therapy is associated with reduced coronary inflammation on CT in patients with type 2 diabetes mellitus

Diabetes, Obesity and Metabolism, Volume 27, Issue 11, Page 6395-6402, November 2025.
Abstract Aims Pericoronary adipose tissue (PCAT) attenuation, assessed by coronary computed tomography angiography (CCTA), is a biomarker of coronary inflammation. Mean PCAT attenuation ≥ −70.5 Hounsfield Units (HU) corresponds to elevated inflammation and a higher future risk of myocardial infarction.
Bryan Wu, Koen Nieman, Ryan Sandoval
wiley   +1 more source

Coronary Inflammation by Computed Tomography Pericoronary Fat Attenuation in MINOCA and Tako‐Tsubo Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The pericoronary fat attenuation index (pFAI) has emerged as a marker of coronary inflammation, which is measurable from standard coronary computed tomography angiography (CCTA).
Nicola Gaibazzi, Chiara Martini, Andrea Botti, Antonio Pinazzi, Barbara Bottazzi, Anselmo A. Palumbo   +5 more
doaj   +1 more source

Spectral Imaging Techniques in Heart Disease Assessment Using Photon‐Counting Detector Computed Tomography

Echocardiography, Volume 42, Issue 8, August 2025.
ABSTRACT The photon‐counting detector (PCD) system was developed to overcome the limitations of traditional energy‐integrating detectors (EIDs) in computed tomography. This technique results in a higher contrast‐to‐noise ratio (CNR), better spatial resolution, and additionally provides detector‐based spectral information.
Sámuel Beke, Emese Zsarnóczay, Lili Száraz, Borbála Vattay, Dmitrij Kravchenko, Milan Vecsey‐Nagy, Giuseppe Tremamunno, Tilman Emrich, Akos Varga‐Szemes, Bálint Szilveszter, Pál Maurovich‐Horvat   +10 more
wiley   +1 more source

Epicardial Fat: Physiological, Pathological, and Therapeutic Implications

Cardiology Research and Practice, Volume 2016, Issue 1, 2016., 2016
Epicardial fat is closely related to blood supply vessels, both anatomically and functionally, which is why any change in this adipose tissue’s behavior is considered a potential risk factor for cardiovascular disease development. When proinflammatory adipokines are released from the epicardial fat, this can lead to a decrease in insulin sensitivity ...
Juan Salazar, Eliana Luzardo, José Carlos Mejías, Joselyn Rojas, Antonio Ferreira, José Ramón Rivas-Ríos, Valmore Bermúdez, Anne Knowlton   +7 more
wiley   +1 more source

Inflammation in atherosclerotic cardiovascular disease: From diagnosis to treatment

European Journal of Clinical Investigation, Volume 55, Issue 7, July 2025.
Inflammation in atherosclerotic cardiovascular disease. Residual inflammatory risk (RIR), defined by high‐sensitive C‐reactive protein (hsCRP) concentration of ≥2 mg/L, represents a strong predictor of future atherosclerotic cardiovascular disease (ASCVD) events. Although increased hsCRP values ≥2 mg/L might be detected in every three out of five ASCVD
Natalie Arnold, Wolfgang Koenig
wiley   +1 more source

Noninvasive Assessment of Coronary Artery Disease: Recent Techniques, Diagnostic Accuracy, and Clinical Implications for Modern Cardiology–A Narrative Review

Health Science Reports, Volume 8, Issue 3, March 2025.
ABSTRACT Background and Aims Coronary artery disease (CAD), a leading cause of death globally, is among the most commonly diagnosed manifestations of heart disease. Although invasive coronary angiography (ICA) remains the “gold standard” to detect CAD, it is accompanied by several limitations.
Dionysia Kravarioti, Hassan Chaito, Souhail Ouardouz, Elaf Abdulnaser Al‐Saab, Magda Wojtara, Olivier Uwishema   +5 more
wiley   +1 more source