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Perimenopause and Cognition [PDF]
Obstetrics and Gynecology Clinics of North America, 2011 The impact of perimenopause on cognition seems to be characterized by an absence of improved scores rather than a decline. In the SWAN, the perimenopausal decrement in cognitive performance was not accounted for; however, increases in anxiety and depressive symptoms had independent, unfavorable effects on performance.
Gail A Greendale +2 more
exaly +3 more sources
Body composition and cardiometabolic risk reduction following therapy with a multi-ingredient nutraceutical formulation: a real-life clinical study [PDF]
Drugs in ContextBackground: Women in perimenopause or postmenopause experience an increased susceptibility to cardiometabolic disorders due to hormonal and physiological changes.
Anna Maria Sironi +3 more
doaj +2 more sources
Steroid Hormone Secretion Over the Course of the Perimenopause: Findings From the Swiss Perimenopause Study [PDF]
Frontiers in Global Women's Health, 2021 Background: Perimenopause is characterized by a decline in the steroid hormones, estradiol, and progesterone. By contrast, the steroid hormone cortisol, a marker of the hypothalamic–pituitary–adrenal (HPA) axis, increases.
Jessica Grub +7 more
doaj +2 more sources
Journal of Affective Disorders, 2020 BACKGROUND: There is a prevalence peak of depression in the perimenopause, with this reproductive phase being considered a window of vulnerability due to major biopsychosocial changes.
Jasmine Willi +2 more
exaly +2 more sources
Bone and the Perimenopause [PDF]
Obstetrics and Gynecology Clinics of North America, 2011 Loss of ovarian function has a profound impact on female skeletal health. Bone mineral density findings from the Study of Women's Health Across the Nation demonstrate an accelerated rate of bone loss during the menopausal transition. The greatest reduction occurs in the year before the final menstrual period and the first 2 years thereafter.
Joan C Lo +2 more
exaly +3 more sources
‘They can induce and exacerbate each other’ – the complex interplay between domestic abuse and the perimenopause: a qualitative study with female survivors [PDF]
BMC Women's HealthBackground Domestic abuse (DA) and perimenopause are each known to profoundly impact women’s health, yet their intersection remains largely unexplored.
Claire Mann +2 more
doaj +2 more sources
Current therapy in endocrinology and metabolism, 1997 The perimenopause is an extremely important time in a woman's life. In a similar but reverse sequence to puberty, it signals a change in ovarian status.
Lobo, Rogerio A.
core +4 more sources
The perimenopause, depressive disorders, and hormonal variability
São Paulo Medical JournalCONTEXT: Several investigations have postulated that the perimenopause may represent a period of increased psychiatric vulnerability, particularly for mood disorders.
Cláudio de Novaes Soares +1 more
doaj +2 more sources
Perimenopause symptoms, severity, and healthcare seeking in women in the US
npj Women's HealthPerimenopause is the transition through menopause and is associated with many symptoms, which can impact daily functioning. Many people who menstruate feel unprepared as they approach menopause, highlighting the need for research into the experience of ...
Adam C. Cunningham +5 more
doaj +2 more sources
Perimenopause Decreases SERCA2a Activity in the Hearts of a Mouse Model of Ovarian Failure
BiomoleculesRisk of cardiovascular disease mortality rises in women after menopause. While increased cardiovascular risk is largely attributed to postmenopausal declines in estrogens, the molecular changes in the heart that contribute to risk are poorly understood ...
Ciara Barry +5 more
doaj +2 more sources