Results 151 to 160 of about 413,356 (306)

Adeno‐associated virus‐mediated restoration of NaV1.1 in targeted brain regions ameliorates epilepsy in symptomatic Dravet syndrome mice

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a developmental and epileptic encephalopathy primarily caused by haploinsufficiency of the SCN1A gene, which encodes the alpha subunit of NaV1.1 voltage‐gated sodium channel. The disease manifests with febrile and spontaneous seizures, developmental delay, cognitive impairment, and increased risk of sudden ...
Martina Mainardi, Simone Brusco, Serena Gea Giannelli, Vania Broccoli, Gaia Colasante   +4 more
wiley   +1 more source

Anàlisi de les dades bàsiques de salut a l'etapa perinatal

, 2010
Salut perinatal; Estadístiques; Catalunya; Perinatal care; Statistics; Catalonia; Salud perinatal; Estadísticas; CataluñaLes dades que es presenten en aquest document provenen del monitoratge de salut perinatal que es realitza sistemàticament mitjançant ...

core  

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

The effect of nighttime or weekend births on perinatal outcomes in Africa, 2025: Systematic review and meta-analysis. [PDF]

Matern Health Neonatol Perinatol
Melesse YD, Mihiret GT, Fetene MG, Amha H, Getnet A, Gete M, Ewunetie AA, Abneh AA, Gedif G, Lamesgen A, Kassie TD, Bitewa MD, Alamneh AA, Siferih M, Muluneh AA.   +14 more
europepmc   +1 more source

Perinatal pharmacology [PDF]

Seminars in Fetal and Neonatal Medicine, 2013
John van den Anker, Karel Allegaert
openaire   +2 more sources

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

The long-term course of perinatal anxiety: A systematic review and meta-analysis protocol. [PDF]

PLoS One
McGuinness RZJ, Fairbrother N, Challacombe FL.   +2 more
europepmc   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Mapping methodological approaches in perinatal health and wellbeing research involving Aboriginal and Torres Strait Islander women: a scoping review protocol. [PDF]

BMJ Open
McCalman R, Khaw S, Bowman A, Garti I, Roe Y.   +4 more
europepmc   +1 more source