Results 1 to 10 of about 210,014 (238)

Perinatal asphyxia and hypothermic treatment from the endocrine perspective [PDF]

Frontiers in Endocrinology, 2023
IntroductionPerinatal asphyxia is one of the three most important causes of neonatal mortality and morbidity. Therapeutic hypothermia represents the standard treatment for infants with moderate-severe perinatal asphyxia, resulting in reduction in the ...
Nicola Improda, Nicola Improda, Donatella Capalbo, Antonella Poloniato, Gisella Garbetta, Francesco Dituri, Laura Penta, Tommaso Aversa, Linda Sessa, Francesco Vierucci, Mariarosaria Cozzolino, Maria Cristina Vigone, Giulia Maria Tronconi, Marta del Pistoia, Laura Lucaccioni, Gerdi Tuli, Gerdi Tuli, Jessica Munarin, Jessica Munarin, Daniele Tessaris, Daniele Tessaris, Luisa de Sanctis, Luisa de Sanctis, Mariacarolina Salerno   +23 more
doaj   +3 more sources

Divergent epigenetic responses to perinatal asphyxia in severe mental disorders [PDF]

Translational Psychiatry
Epigenetic modifications influenced by environmental exposures are molecular sources of phenotypic heterogeneity found in schizophrenia and bipolar disorder and may contribute to shared etiopathogenetic mechanisms of these two disorders.
Laura A. Wortinger, Anne-Kristin Stavrum, Alexey A. Shadrin, Attila Szabo, Sondre Høeg Rukke, Stener Nerland, Runar Elle Smelror, Kjetil Nordbø Jørgensen, Claudia Barth, Dimitrios Andreou, Melissa A. Weibell, Srdjan Djurovic, Ole A. Andreassen, Marianne Thoresen, Gianluca Ursini, Ingrid Agartz, Stephanie Le Hellard   +16 more
doaj   +3 more sources

Neonatal mortality associated with perinatal asphyxia: a population-based study in a middle-income country

BMC Pregnancy and Childbirth, 2021
Background It is challenging to decrease neonatal mortality in middle-income countries, where perinatal asphyxia is an important cause of death. This study aims to analyze the annual trend of neonatal mortality with perinatal asphyxia according to ...
Mandira D. Kawakami, Adriana Sanudo, Mônica L. P. Teixeira, Solange Andreoni, Josiane Q. X. de Castro, Bernadette Waldvogel, Ruth Guinsburg, Maria Fernanda de Almeida   +7 more
doaj   +2 more sources

Perinatal asphyxia and associated factors among neonates admitted to a specialized public hospital in South Central Ethiopia: A retrospective cross-sectional study.

PLoS ONE, 2022
IntroductionPerinatal asphyxia continues to be a significant clinical concern around the world as the consequences can be devastating. World Health Organization data indicates perinatal asphyxia is encountered amongst 6-10 newborns per 1000 live full ...
Seifu Awgchew Mamo, Girum Sebsibie Teshome, Tewodros Tesfaye, Abel Tibebu Goshu   +3 more
doaj   +2 more sources

Networks of cortical activity show graded responses to perinatal asphyxia. [PDF]

Pediatr Res, 2023
Perinatal asphyxia often leads to hypoxic-ischemic encephalopathy (HIE) with a high risk of neurodevelopmental consequences. While moderate and severe HIE link to high morbidity, less is known about brain effects of perinatal asphyxia with no or only ...
Syvälahti T, Tuiskula A, Nevalainen P, Metsäranta M, Haataja L, Vanhatalo S, Tokariev A.   +6 more
europepmc   +2 more sources

Metabolomics to Diagnose Oxidative Stress in Perinatal Asphyxia: Towards a Non-Invasive Approach

Antioxidants, 2021
There is a need for feasible and non-invasive diagnostics in perinatal asphyxia. Metabolomics is the study of small molecular weight products of cellular metabolism that may, directly and indirectly, reflect the level of oxidative stress. Saliva analysis
Anne Lee Solevåg, Svetlana N. Zykova, Per Medbøe Thorsby, Georg M. Schmölzer   +3 more
doaj   +2 more sources

Prevalence and associated factors of perinatal asphyxia in newborns admitted to neonatal intensive care unit at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, Ethiopia

BMC Pediatrics, 2021
Background Perinatal asphyxia is one of the leading causes of neonatal mortality and morbidity in Ethiopia. Understanding associated factors of perinatal asphyxia are important to identify vulnerable groups and to improve care during the perinatal period.
Addisu Ginbu Dubie, Mehretie Kokeb, Abraham Tarkegn Mersha, Chilot Desta Agegnehu   +3 more
doaj   +2 more sources

Prevalence and Associated Factors of Perinatal Asphyxia in Neonates Admitted to Ayder Comprehensive Specialized Hospital, Northern Ethiopia: A Cross-Sectional Study

International Journal of Pediatrics, 2020
Background. Perinatal asphyxia is defined as the inability of the newborn to initiate and sustain enough respiration after delivery and is characterized by a marked impairment of gas exchange. It is one of the most common causes of neonatal mortality and
Gebrehiwot Teklehaimanot Gebregziabher, Fikaden Berhe Hadgu, Haftom Temesgen Abebe   +2 more
doaj   +2 more sources

Pathophysiology of Perinatal Asphyxia in Humans and Animal Models

Biomedicines, 2022
Perinatal asphyxia is caused by lack of oxygen delivery (hypoxia) to end organs due to an hypoxemic or ischemic insult occurring in temporal proximity to labor (peripartum) or delivery (intrapartum).
Daniel Mota-Rojas, Ramon Muns Vila, Daniel Ibarra-Ríos   +2 more
exaly   +2 more sources

Exploring Perinatal Asphyxia by Metabolomics [PDF]

Metabolites, 2020
Brain damage related to perinatal asphyxia is the second cause of neuro-disability worldwide. Its incidence was estimated in 2010 as 8.5 cases per 1000 live births worldwide, with no further recent improvement even in more industrialized countries. If so, hypoxic-ischemic encephalopathy is still an issue of global health concern.
Emanuela Locci, Giovanni Bazzano, Roberto Demontis, Alberto Chighine, Vassilios Fanos, Ernesto d'Aloja   +5 more
openaire   +5 more sources