Results 51 to 60 of about 157,949 (196)

Networks of cortical activity show graded responses to perinatal asphyxia. [PDF]

Pediatr Res, 2023
Background: Perinatal asphyxia often leads to hypoxic-ischemic encephalopathy (HIE) with a high risk of neurodevelopmental consequences. While moderate and severe HIE link to high morbidity, less is known about brain effects of perinatal asphyxia with no
Syvälahti T, Tuiskula A, Nevalainen P, Metsäranta M, Haataja L, Vanhatalo S, Tokariev A.   +6 more
europepmc   +2 more sources

Neonatal resuscitation and immediate newborn assessment and stimulation for the prevention of neonatal deaths: a systematic review, meta-analysis and Delphi estimation of mortality effect. [PDF]

, 2011
BACKGROUND: Of 136 million babies born annually, around 10 million require assistance to breathe. Each year 814,000 neonatal deaths result from intrapartum-related events in term babies (previously "birth asphyxia") and 1.03 million from complications of
Carlo, Waldemar A, Bhutta Zulfiqar A, Darmstadt Gary L, Zulfiqar A Bhutta, Lawn, Joy E, Stephen N Wall, Gary L Darmstadt, Gill Christopher, Wall, Stephen N, Lawn, Joy E., Wall, Stephen N., Lawn Joy E, Joy E Lawn, Darmstadt, Gary L, Niermeyer Susan, Cousens Simon, Simon Cousens, William J Keenan, Lee, Anne CC, Gill, Christopher, Bhutta, Zulfiqar Ahmed, Lee Anne CC, Keenan, William J., Cousens, Simon, Susan Niermeyer, Keenan William J, Darmstadt, Gary L., Wall Stephen N, Bhutta, Zulfiqar A, Keenan, William J, Christopher Gill, Carlo, Waldemar A., Anne CC Lee, Carlo Waldemar A, Niermeyer, Susan, Lee, Anne C. C., Waldemar A Carlo   +36 more
core   +1 more source

Machine learning models based on clinical indices and cardiotocographic features for discriminating asphyxia fetuses—Porto retrospective intrapartum study

Frontiers in Public Health, 2023
IntroductionPerinatal asphyxia is one of the most frequent causes of neonatal mortality, affecting approximately four million newborns worldwide each year and causing the death of one million individuals. One of the main reasons for these high incidences
Maria Ribeiro, Maria Ribeiro, Inês Nunes, Inês Nunes, Inês Nunes, Luísa Castro, Luísa Castro, Cristina Costa-Santos, Teresa S. Henriques   +8 more
doaj   +1 more source

Model‐Informed Dose Optimization of Anakinra in Preterm Neonates Implications for Safe and Effective Dosing

Clinical Pharmacology &Therapeutics, EarlyView.
Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li, David K. Metz, Elys Green, Gergely Toldi, Robert Galinsky, Megan Clark, Rebecka Atkinson, Ina Rudloff, Josephine C. Owen, Sara K. DiSimone, Samuel C. Forster, Steven X. Cho, Atif Majid, Graeme R. Polglase, Marcel Favilla, Pramod Pharande, Atul Malhotra, Calum T. Roberts, Scott H. Stansfield, Arvind Sehgal, Kenneth Tan, Alistair J. Gunn, Philip J. Berger, Alex Veldman, Rod W. Hunt, Claudia A. Nold‐Petry, Marcel F. Nold, Carl M. J. Kirkpatrick   +27 more
wiley   +1 more source

Características bioquímicas e citologia do líquido cefalorraquidiano de recém-nascidos a termo com asfixia perinatal [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em Ciências Médicas.OBJETIVOS: Descrever as características do líquido cefalorraquidiano (análise bioquímica - proteína e glicose, e ...
Koneski, Júlio Amaro de Sá
core  

Astrocyte subtype‐specific alterations in the dentate gyrus of individuals with mesial temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch, Jakob Johann Schmidt, Daniel Delev, Roland Coras, Ingmar Blümcke, Ruth Beckervordersandforth   +5 more
wiley   +1 more source

Dystonia Due to Perinatal Asphyxia

, 1991
Delayed onset dystonia associated with perinatal asphyxia in two patients and asphyxia in early childhood in two patients is reported from the Neurological Institute of New ...
J Gordon Millichap
core   +1 more source

Predictors of mortality among newborns admitted with perinatal asphyxia at public hospitals in Ethiopia: a prospective cohort study

BMC Pediatrics, 2021
Introduction Perinatal asphyxia is a complicated newborn health problem and applies a high contribution to the increased proportion of newborn mortality.
Samuel Dessu, Zinabu Dawit, Abebe Timerga, Muluken Bafa   +3 more
doaj   +1 more source

Renal Functions in Relation to Severity of Perinatal Asphyxia in Term Neonates [PDF]

Indian Journal of Neonatal Medicine and Research, 2020
Introduction: Kidney is one of the most important organs commonly involved in the multiple organ dysfunction caused by perinatal asphyxia. Monitoring the serum urea, creatinine and urine output helps in early assessment of severity of perinatal asphyxia ...
Dinesh Kumar, Mukesh Vir Singh, Niraj Kumar, Durgesh Kumar, Krishan Mohan Shukla, Kalbe Jawad   +5 more
doaj   +1 more source

Evaluating predictive values of umbilical cord arterial lactate for adverse newborn outcomes among term‐births in northern Uganda: A cross sectional analytical study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 408-420, April 2025.
Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare, James K. Tumwine, Jolly Nankunda, Anna Hjelmstedt, Wibke Jonas, Grace Ndeezi, Nicola Orsini, Claudia Hanson   +7 more
wiley   +1 more source