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The Iowa Perinatal Letter, January-February-March 2007, Vol. 28, no.1 [PDF]

, 2007
This newsletter from The Department of Public Health about perinatal health care and ...

core  

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Progeny, December 2012, Vol. 28, no. 4 [PDF]

, 2012
This newsletter from The Department of Public Health about perinatal health care and ...

core  

Seeking help for perinatal psychological distress: a meta-synthesis of women's experiences [PDF]

, 2017
Background Women may not seek help for perinatal psychological distress, despite regular contact with primary care services. Barriers include ignorance of symptoms, inability to disclose distress, others’ attitudes, and cultural expectations.
Alexandra Thornton, Ayers, Boath, Briscoe, Chew-Graham, Cooke, Edge, Edge, Edge, Edge, Gardner, Hall, Hanley, Hanley, Hannan, Iles, Judy Shakespeare, Mauthner, Mauthner, Patel, Premji, Rickwood, Shakespeare, Susan Ayers, Susan Button, Suzanne Lee   +25 more
core   +1 more source

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

Advanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao, Yajie Peng, Hongyan Lei, Tianyi Wang, Huajuan Wang, Bo Wang, Jin Li, Xiaoying Li, Xuelian Xiong   +8 more
wiley   +1 more source

The Iowa Perinatal Letter, January-February-March 2009, Vol. 30, no. 1 [PDF]

, 2009
This newsletter from The Department of Public Health about perinatal health care and ...

core  

Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis [PDF]

, 2018
Introduction: The age of diagnosis of Huntington's disease (HD) varies among individuals with the same HTT CAG-repeat expansion size. We investigated whether early-life events, like perinatal insults or neurodevelopmental disorders, influence the ...
Anderson, Dg, Barkhuizen, M, Ferraldeschi, M, Gavilanes, Awd., Kramer, Bw, REGISTRY Investigators of the European Huntington's Disease, Network, Ristori, G, Rodrigues, Fb, Romano, S, Wild, Ej, Winkens, B   +10 more
core   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Low-dose epidural morphine for postpartum pain relief: a randomized, single-blind study

JA Clinical Reports
Introduction Epidural morphine administration following vaginal delivery reduces postpartum pain; however, side effects may occur. We investigated whether a lower dose could achieve pain relief without increasing the incidence and severity of side ...
Hiroaki Kondo, Shunsuke Hyuga, Yoshinori Tomoda, Tomoe Fujita, Mariko Adachi, Toshiyuki Okutomi   +5 more
doaj   +1 more source

Recognition and CBT for Paternal Perinatal Depression in Primary Care: A Case Report

American Journal of Men's Health, 2023
Perinatal depression is prevalent in primary care in the United Kingdom. The recent NHS agenda implemented specialist perinatal mental health services to improve women’s access to evidence-based care.
Lilian Skilbeck, Christopher Spanton, Ian Roylance   +2 more
doaj   +1 more source