Results 51 to 60 of about 2,052,438 (257)

The value of fetal Doppler indices as predictors of perinatal outcome in women with preeclampsia with severe features

Hypertension in Pregnancy, 2020
Objective To evaluate the diagnostic performance of Doppler sonography of umbilical artery (UA), fetal middle cerebral artery (MCA), ductus venosus (DV) & umbilical vein (UV) for prediction of adverse perinatal outcome. Material and Methods A prospective
Nihal M. El-Demiry, Ahmed M. Maged, Hassan M. Gaafar, Sherif ElAnwary, Amany Shaltout, Safaa Ibrahim, Hany M. El-Didy, Moutaz M. Elsherbini   +7 more
doaj   +1 more source

Biomarkers of impaired placentation at 35-37 weeks' gestation in the prediction of adverse perinatal outcome [PDF]

, 2019
Objective: This screening study at 35-37 weeks’ gestation investigates the potential value of uterine artery pulsatility index (UtA-PI) and serum levels of the angiogenic placental growth factor (PlGF) and antiangiogenic factor soluble fms-like tyrosine ...
De Castro, H., R. Akolekar, Nicolaides, K. H., L. Frei, A. Ciobanou, Akolekar, R., Frei, L., H. De Castro, Ciobanou, A., K. H. Nicolaides, S. Jabak, Jabak, S.   +11 more
core   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

Color doppler evaluation of cerebral-umbilical pulsatility ratio and its usefulness in the diagnosis of intrauterine growth retardation and prediction of adverse perinatal outcome

Indian Journal of Radiology and Imaging, 2010
Objective: The aim of our study was to evaluate the usefulness of the pulsatility index (PI) of the umbilical artery (UA) and that of the fetal middle cerebral artery (MCA), as well as the ratio of the MCA PI to the UA PI (C/U ratio), in the diagnosis ...
Shahina Bano, Vikas Chaudhary, Sanjay Pande, VL Mehta, AK Sharma   +4 more
doaj   +3 more sources

Perinatal Outcome in Explained and Unexplained Polyhydramnios

Journal of Rawalpindi Medical College, 2013
Background: To compare the perinatal outcome between explained and unexplained (idiopathic) polyhydramnios. Methods: In this descriptive study, 50 women with singleton pregnancies with idiopathic polyhydramnios, delivered in a period of one year, were ...
Maliha Sadaf
doaj  

Therapeutic hypothermia modifies perinatal asphyxia-induced changes of the corpus callosum and outcome in neonates. [PDF]

PLoS ONE, 2015
WHAT IS KNOWN ABOUT THIS SUBJECT?: Diffusion-weighted MRI has demonstrated changes in the corpus callosum of term neonates with perinatal asphyxia. The severity of cerebral changes demonstrated using diffusion-weighted MRI is difficult to assess without ...
Thomas Alderliesten, Linda S de Vries, Yara Khalil, Ingrid C van Haastert, Manon J N L Benders, Corine Koopman-Esseboom, Floris Groenendaal   +6 more
doaj   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18-22 month follow-up for neonatal encephalopathy in a low resource hospital setting in Uganda: study protocol [PDF]

, 2011
Background: There is now convincing evidence that in industrialized countries therapeutic hypothermia for perinatal asphyxial encephalopathy increases survival with normal neurological function. However, the greatest burden of perinatal asphyxia falls in
Allen, Elizabeth, Allen Elizabeth, Cornelia F Hagmann, Jacobs Ian, Hagmann, Cornelia F., Nakakeeto Margaret, Elbourne, Diana, Jacobs, Ian, Ian Jacobs, Costello, Anthony, Frances Cowan, Acolet Dominique, Nicola J Robertson, Acolet, Dominique, Anthony Costello, Cowan Frances, Cowan, Frances, Acolet, D, Elbourne, D, Nyombi, Natasha, Robertson, Nicola J., Hagmann Cornelia F, Dominique Acolet, Robertson Nicola J, Robertson, NJ, Diana Elbourne, Margaret Nakakeeto, Nyombi Natasha, Cowan, F, Jacobs, I, Costello, A, Nakakeeto, Margaret, Robertson, Nicola J, Elbourne Diana, Hagmann, Cornelia F, Nakakeeto, M, Elizabeth Allen, Hagmann, CF, Nyombi, N, Allen, E, Costello Anthony, Natasha Nyombi   +41 more
core   +2 more sources

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source