Results 141 to 150 of about 517,021 (238)

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

SAFE PASSAGES Training Decreased the Incidence of Perineal Trauma During Childbirth. [PDF]

Cureus
Lundeberg KR, Staat B, Crosiar JD, Massengill JC.   +3 more
europepmc   +1 more source

Chronic Scrotal Content Pain: A Practical Guide to Diagnosis and Management

Trends in Urology &Men's Health, Volume 17, Issue 6, December 2026.
ABSTRACT Chronic scrotal content pain (CSCP) is a common but often poorly understood condition that presents a significant diagnostic and therapeutic challenge. The broad differential diagnosis and frequent absence of an identifiable cause can lead to repeated investigations, delayed treatment and unnecessary surgery.
Mahin Chowdhury, Mohammad Arabiyat, Ibrahim Abuelbeh, Theodora Stasinou, Peter Grice, Vaibhav Modgil, Ian Pearce   +6 more
wiley   +1 more source

Antibiotic prophylaxis for childbirth-related perineal trauma: A systematic review and meta-analysis. [PDF]

PLoS One
Armstrong H, Whitehurst J, Morris RK, Hodgetts Morton V, Man R, CHAPTER group.   +5 more
europepmc   +1 more source

The molecular landscape of nodular fasciitis: novel USP6 fusions, genomic stability, and an exploratory clinicopathological model – a 20‐year retrospective study

The Journal of Pathology: Clinical Research, Volume 12, Issue 6, November 2026.
Abstract Nodular fasciitis (NF) is a benign myofibroblastic neoplasm characterized by rapid growth and recurrent USP6 rearrangements. Despite its benign nature, NF may exhibit worrisome histologic or clinical features that mimic sarcoma, posing diagnostic challenges.
Kristijan Skok, Maximilian T Buchwald, Maria Anna Smolle, Theresa Godschachner, Andreas Leithner, Christian Viertler, Bernadette Liegl‐Atzwanger   +6 more
wiley   +1 more source

Effectiveness of Perineal Protection Devices in Reducing Birth-Related Perineal Trauma: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and GRADE Assessment. [PDF]

Int Urogynecol J
Allam S, Abdelkader OKS, Mansour R, Elsayed N, Elshiekh H, Tarabishi J, Hegazy SM, Arafa A, Kertam A.   +8 more
europepmc   +1 more source

Suspected Gluteal Epithelioid Sarcoma Complicated by Secondary Infection and Sciatic Neuropathy: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Secondary infection can coexist with and obscure an underlying soft‐tissue sarcoma. A deep mass that persists or progresses despite drainage and appropriate antibiotics, especially with progressive neurological deficit, warrants image‐guided core biopsy and sarcoma‐center referral before further surgery.
Baraa Nassar, Rawan Omar Nayfeh, Eman Sheikhasan, Saif Khaled Abdalhadi Azzam, Mohammedali Atef Abumayyala   +4 more
wiley   +1 more source

Unusual causes of perineal trauma in paediatric patients: lessons learned from a high-volume colorectal clinic in a low-and-middle-income country. [PDF]

Pediatr Surg Int
Palmisani F, Teko K, Bebington C, Brisighelli G.   +3 more
europepmc   +1 more source

An external validation study of a practical scoring system for identifying patients at risk of pelvic floor dysfunction following childbirth

International Journal of Gynecology &Obstetrics, Volume 175, Issue 2, Page 807-816, November 2026.
Abstract Objective To prospectively evaluate the perineal card, a risk‐based scoring system, for identifying women at increased risk of postpartum urinary incontinence (UI). Methods This prospective observational study included women without previous vaginal delivery who underwent vaginal birth at a tertiary referral center between June 2023 and ...
Martina Arcieri, Michela Segatti, Filippo Bordin, Doriana Armenise, Maria De Martino, Miriam Isola, Chiara Mattiussi, Elisa Barbui, Sara Filippin, Veronica Tius, Cristina Delneri, Valeria Dialti, Stefano Restaino, Lorenza Driul, Giuseppe Vizzielli   +14 more
wiley   +1 more source

Gracilis Muscle Flap Reconstruction for Refractory Urethral Complications After Pelvic Surgery: A Report of Two Cases

IJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Iatrogenic urethral injury and rectourethral fistula are rare and challenging complications of pelvic surgery. Case Presentation Case 1 involved a 72‐year‐old man with persistent urinary leakage after primary repair of a prostatic urethral injury sustained during rectal cancer surgery following neoadjuvant chemoradiotherapy ...
Akihiro Maeda, Shohei Tobu, Minika Yukimoto, Shuhei Kusano, Maki Kawasaki, Hiroaki Kakinoki, Mitsuru Noguchi   +6 more
wiley   +1 more source