Results 151 to 160 of about 13,581,171 (287)

Philippine Clinical Practice Guidelines for Periodic Health Examination: Immunization for Adults. [PDF]

Acta Med Philipp
Masbang AN, Zamora RP, Lardizabal-Bunyi JEL, Razo RA, Punongbayan RB, Bayona HHG, Domingo ALB, Philippine Periodic Health Examination Task Force on Adult Immunization.   +7 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Philippine Clinical Practice Guidelines for Periodic Health Examination: Screening for Cardiovascular Disease. [PDF]

Acta Med Philipp
Oliva RV, Magno JDA, David-Ona DI, Alcaraz JDB, Alcover-Banal JD, Llanes EJB, Leaño BL, Pestaño NS, Pedracio FHLD, Aherrera JAM, Alajar EB, Vicente MA, Gonzales EM, Segundo LPS, Punzalan FER, Philippine Periodic Health Examination Task Force on Screening for Cardiovascular Diseases.   +15 more
europepmc   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Philippine Clinical Practice Guidelines for Periodic Health Examination: Screening for Neoplastic Diseases. [PDF]

Acta Med Philipp
Tiangco BJ, Burog AILD, Garcia-Trinidad AM, Manalo-Igot MO, Loyola AB, Velasco RN, Infantado-Alejandro MAJ, Samala KG, Cacanindin-Rimando JMI, Bayona HHG, Eubanas GAS, Patdu MPD, Philippine Periodic Health Examination Task Force on Neoplastic Diseases.   +12 more
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Philippine Clinical Practice Guidelines for Periodic Health Examination: Screening for Hearing Disorders. [PDF]

Acta Med Philipp
Carrillo RJD, Salcedo AS, Pascual V JLR, Alcances LRA, Baltazar-Braganza K, Murillo KJE, Cruz-Tantoco MG, Imbag MDS, Collante MTM, Tan CAY, Joson MVASG, Alonzo MKP, Adique LCF, Andal-Saniano AC, Catangay-Ombao JV, Cucueco MTS, De Ramos JSM, Cruz EMD, Lacuata JAC, Canceko-Llego C, Ong KMC, Ramos HD, Reyes-Quintos MRT, Ricalde RR, Yarza TKL, Philippine Periodic Health Examination Task Force on Screening for Hearing Disorders.   +25 more
europepmc   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Philippine Clinical Practice Guidelines for Periodic Health Examination: Screening for Infectious Diseases. [PDF]

Acta Med Philipp
Garcia JU, Zamora RP, Manalo CG, Pimentel JMT, Fajardo ASVS, Andal-Saniano A, Payawal DA, Philippine Periodic Health Examination Task Force on Screening for Infectious Diseases.   +7 more
europepmc   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source