Results 121 to 130 of about 1,516,190 (385)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Research on a Ka‐band large‐orbit gyro‐TWT with periodic dielectric‐loaded structure

open access: yesElectronics Letters
This paper presents a design of a gyro‐TWT operating in the large‐orbit electron beam mode, with the aim of reducing the working magnetic field while ensuring operational efficiency.
Yang Jintao   +6 more
doaj   +1 more source

Hopf bifurcation for a class of predator-prey system with small immigration

open access: yesElectronic Research Archive
The subject of this paper concerns with the bifurcation of limit cycles for a predator-prey model with small immigration. Since, in general, the biological systems are not isolated, taking into account immigration in the model becomes more realistic.
Maurıicio F. S. Lima, Jaume Llibre
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Screen chaotic motion by Shannon entropy in curved spacetimes

open access: yesEuropean Physical Journal C: Particles and Fields
We find a novel characteristic for chaotic motion by introducing Shannon entropy for periodic orbits, quasiperiodic orbits, and chaotic orbits. We compare our approach with the previous methods including Poincaré section, Lyapunov exponent, fast Lyapunov
Wenfu Cao, Yang Huang, Hongsheng Zhang
doaj   +1 more source

Behavior near a periodic orbit of functional differential equations [PDF]

open access: yes
Behavior near periodic orbit of functional differential ...
Hale, J. K.
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A Disk-originated 329 Day Quasiperiodic Oscillation in the Seyfert 1 Galaxy J1626+5120

open access: yesThe Astrophysical Journal Letters
The Seyfert 1 galaxy J1626+5120 is estimated to host a 10 ^8 M _⊙ black hole (BH) accreting at Eddington ratio ${\dot{m}}_{\,\rm{Edd}\,}\approx 0.043$ . Its long-term multiband light-curve data show flicker-like variations, but in a well-sampled g -band ...
Litao Zhu   +4 more
doaj   +1 more source

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