Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont+4 more
wiley +1 more source
Characterization of Hydraulic Rock Diffusivity Using Oscillatory Pore Pressure. [PDF]
Sciandra D+4 more
europepmc +1 more source
Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period
ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad+15 more
wiley +1 more source
Optical solitons, bifurcation, and chaos in the nonlinear conformable Schrödinger equation with group velocity dispersion coefficients and second-order spatiotemporal terms. [PDF]
Omar FM+4 more
europepmc +1 more source
Periodic solutions of conservation laws
openaire +3 more sources
Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck+15 more
wiley +1 more source
Bifurcation analysis, modulation instability and dynamical analysis of soliton solutions for generalized (3 + 1)-dimensional nonlinear wave equation with m-fractional operator. [PDF]
Algolam MS+5 more
europepmc +1 more source
The Road Not Taken: Misclassifying an Anti‐Seizure Medication as a Failure
ABSTRACT Objective To quantify how often anti‐seizure medications (ASMs) appear ineffective yet provide benefit when considering seizure frequency (SF) variability. Methods We used the CHOCOLATES seizure diary simulator to generate 100,000 patient seizure diaries that reflect natural SF variation in a heterogeneous population.
Christopher N. Henry+1 more
wiley +1 more source
Entropy Generation Optimization in Multidomain Systems: A Generalized Gouy-Stodola Theorem and Optimal Control. [PDF]
Richter H, Fathizadeh M, Kaptain T.
europepmc +1 more source