Results 61 to 70 of about 15,821 (256)

On a Second-Order Difference Equation with Two Periodic Coefficients

Axioms
This work focuses on a class of nonlinear second-order difference equations with non-autonomous periodic coefficients. We obtain explicit solution formulas that allow for a constructive characterization of their behavior.
Lama Sh. Aljoufi, Nouressadat Touafek, Elsayed M. Elsayed   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Existence of periodic solutions for higher-order nonlinear difference equations

Electronic Journal of Differential Equations, 2016
In this article, we study a higher-order nonlinear difference equation. By using critical point theory, we establish sufficient conditions for the existence of periodic solutions.
Jianhua Leng
doaj  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Periodic solutions of a discrete-time diffusive system governed by backward difference equations

Advances in Difference Equations, 2005
A discrete-time delayed diffusion model governed by backward difference equations is investigated. By using the coincidence degree and the related continuation theorem as well as some priori estimates, easily verifiable sufficient criteria are ...
Jiezhong Zou, Binxiang Dai
doaj   +2 more sources

A difference equation with eventually periodic solutions

Computers & Mathematics with Applications, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Amleh, A.M., Hoag, J., Ladas, G.
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Reverse-Order Lower and Upper Functions for Periodic Problems of Second-Order Singular Difference Equations

Abstract and Applied Analysis, 2013
We present sufficient conditions ensuring the lower and upper functions on the reversed-order for the periodic difference equations. This enables us to obtain the existence of positive periodic solutions of the second-order difference equation where ...
Yanqiong Lu, Ruyun Ma
doaj   +1 more source

Existence of positive periodic solutions for higher order singular functional difference equations

Electronic Journal of Qualitative Theory of Differential Equations, 2014
We study a higher order singular functional difference equation on $\mathbb{Z}$. Sufficient conditions are obtained for the existence of at least one positive periodic solution of the equation.
Jacob Johnson, Lingju Kong, Michael Ruddy, Alexander Ruys De Perez   +3 more
doaj   +1 more source

On the periodicity of the solution of a rational difference equation

Communications Faculty Of Science University of Ankara Series A1Mathematics and Statistics, 2019
Summary: In this paper, some cases on the periodicity of the rational difference equation \[S_{n+1} = S_{n-p}\left(\frac{aS_{n-q} + bS_{n-r} +cS_{n-s}}{dS_{n-q}+ eS_{n-r} + fS_{n-s}}\right),\] are investigated, where \(a, b, c, d, e, f\in(0,\infty)\).
Alotaibi, A. M., Noorani, M. S. M., El-moneam, M. A.   +2 more
openaire   +4 more sources