Results 51 to 60 of about 23,176 (145)
Biotechnology and Bioengineering, EarlyView.ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal +2 more
wiley +1 more source
Are physiological oscillations physiological?
The Journal of Physiology, EarlyView., 2023 Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley +1 more source
Decay estimate of viscosity solutions of nonlinear parabolic PDEs and applications
Le Matematiche, 2014 The aim of this paper is to establish a decay estimate for viscosity solutions of nonlinear PDEs. As an application we prove existence and uniqueness for time almost periodic viscosity solutions.
Silvana Marchi
doaj
Rigorous a-posteriori analysis using numerical eigenvalue bounds in a surface growth model
, 2017 In order to prove numerically the global existence and uniqueness of smooth solutions of a fourth order, nonlinear PDE, we derive rigorous a-posteriori upper bounds on the supremum of the numerical range of the linearized operator. These bounds also have
Blömker, Dirk, Nolde, Christian
core +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Chronic thromboembolic pulmonary disease (CTEPD) leads to chronic total occlusions (CTOs) of the pulmonary arteries in a minority of patients. Treatment of CTOs with balloon pulmonary angioplasty (BPA) may substantially improve patient hemodynamics but presents unique technical challenges and has previously been associated with a ...
Elliot J. Stein +4 more
wiley +1 more source
Optimization of 3D‐Printed Structured Packings—Current State and Future Developments
Chemie Ingenieur Technik, EarlyView.This paper gives an overview about structured packing development for distillation, surveying heuristic development cycles, computational fluid dynamics simulations, and additive manufacturing techniques. The emerging application of shape optimization to improve packings is emphasized, and its benefits, impact, and limitations are discussed.
Dennis Stucke +3 more
wiley +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.Abstract We develop a delay‐aware estimation and control framework for a non‐isothermal axial dispersion tubular reactor modelled as a coupled parabolic‐hyperbolic PDE system with recycle‐induced state delay. The infinite‐dimensional dynamics are preserved without spatial discretization by representing the delay as a transport PDE and adopting a late ...
Behrad Moadeli, Stevan Dubljevic
wiley +1 more source
Invariant Measure and Universality of the 2D Yang–Mills Langevin Dynamic
Communications on Pure and Applied Mathematics, EarlyView.ABSTRACT We prove that the Yang–Mills (YM) measure for the trivial principal bundle over the two‐dimensional torus, with any connected, compact structure group, is invariant for the associated renormalised Langevin dynamic. Our argument relies on a combination of regularity structures, lattice gauge‐fixing and Bourgain's method for invariant measures ...
Ilya Chevyrev, Hao Shen
wiley +1 more source
Deep Underground Science and Engineering, EarlyView.The evolution of the temperature field and frozen wall under different fracture conditions was examined by an artificial ground freezing‐based thermal‐hydraulic coupled model. It was observed that fracture inclination affects the interaction extent of freezing pipes and fracture, while phase transition extent is the dominant factor for heat transfer in
Chenyi Zhang +9 more
wiley +1 more source
The Perturbed Chen–Lee–Liu Equation: Diverse Optical Soliton Solutions and Other Wave Solutions
Advances in Mathematical PhysicsThe objective of the present study is to extract the optical soliton solutions (OSSs) of the perturbed Chen–Lee–Liu equation by exerting three techniques, which are the extended Wang’s direct mapping method, tanh/coth function method and the Subequation ...
Kang-Jia Wang
doaj +1 more source