Results 41 to 50 of about 15,006,822 (290)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The origins of the Greek periodical press [PDF]
, 2017 This study deals with the first Greek periodical press which emerged initially outside of Greece. Historical periodisation and some circumstances connected to the distribution of the first journals introduce the topic at the beginning.
Knapková, Kristýna
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношенияIntroduction. The topics of scientific and qualification works of the beginning of the 21st century reflect a multifactorial approach to the study of Russian regional history.
Nadezhda Archebasova
doaj +1 more source
DATA OF J. JÄHRIG IN FOREIGN PERIODICAL PRESS AT THE END OF XVIII - BEGINNING OF XIX CENTURIES
Гуманитарные и юридические исследования, 2021 The article describes analysis of the foreign periodical press materials at end of XVIII -first half of the XIX century. These materials of the interpreter of the Russian Academy of Sciences Johannes Jährig contain his reports about culture and religion ...
A. A. Diuldenko
doaj
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Review of: The Indian Periodical Press And The Production Of Nationalist Rhetoric by Sukeshi Kamra
, 2013 The article reviews the book The Indian Periodical Press and the Production of Nationalist Rhetoric by Sukeshi ...
Joshi, Priti
core +1 more source