Results 121 to 130 of about 127,295 (353)

Writing Effective Paragraphs

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2016
Taking a methodical approach to constructing paragraphs can improve clarity and organization in medical writing. This article describes a typical model for paragraph structure, explains the significance of coherence and cohesion, and recommends revision ...
Kristin Messuri
doaj  

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash   +6 more
wiley   +1 more source

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

open access: yesFEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi   +2 more
wiley   +1 more source

Manual search approaches used by systematic reviewers in dermatology

open access: yesJournal of the Medical Library Association, 2017
Objective: Manual searches are supplemental approaches to database searches to identify additional primary studies for systematic reviews. The authors argue that these manual approaches, in particular hand-searching and perusing reference lists, are ...
Matt Vassar   +2 more
doaj   +1 more source

Reading In The Farm Home [PDF]

open access: yes, 1919
Exact date of bulletin unknown.PDF pages ...
Graves, William L.
core  

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

Topics on periodic solutions to integro-differential equations

open access: yes, 2020
This Master's Degree Thesis investigates periodic solutions to nonlinear equations involving integro-dierential operators. We show the existence and we describe these solutions for generalized Benjamin-Ono type nonlinearities, using a variational formulation and a constrained minimization argument.
openaire   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Creating a Comprehensive Review of the Literature [PDF]

open access: yes, 2019
Research normally begins by doing a “review of the literature” to see what has already been written and to determine “gaps” in the literature for further research. This handout reviews ways to search for books, scholarly articles, dissertations, and grey
Miller, Randy L
core   +1 more source

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