Results 61 to 70 of about 184,923 (284)

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

The dental management of patients at risk of medication-related osteonecrosis of the jaw: New paradigm of primary prevention [PDF]

open access: yes, 2018
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is a potentially painful and debilitating condition that can considerably affect the quality of life of patients ...
Bedogni, Alberto   +7 more
core   +2 more sources

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

open access: yesAdvanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim   +11 more
wiley   +1 more source

Antioxidantes dietéticos para la prevención de la periodontitis crónica y su tratamiento. Una revisión de las evidencias actuales procedentes de estudios en animales y humanos [PDF]

open access: yes, 2015
Objetivos. Dada la relación existente entre periodontitis crónica y altos niveles de estrés oxidativo, esta revisión pretende clarificar qué papel puede desempeñar la ingesta de los diferentes antioxidantes de la dieta en el mantenimiento de un ...
Bullon, Pedro
core  

Periodontal disease and cardiovascular disease [PDF]

open access: yesEvidence-Based Dentistry, 2004
Data sources Medline (1980–present) and bibliographic citations from each article were consulted to find relevant studies. Study selection Analyses were restricted to cohort studies published between 1980 and February 2001 so that any effects of secular trends could be minimised.
openaire   +2 more sources

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

open access: yesAdvanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck   +8 more
wiley   +1 more source

Periodontitis and the Elderly: An Overview of the Disease and its Impact on an Aging Population [PDF]

open access: yes, 2019
Periodontitis affects millions of Americans each year, and is especially prevalent among the elderly. Since periodontitis is a chronic, progressive condition, uninterrupted disease progression leads to irreversible oral damage; therefore, periodontitis ...
Weissenfluh, Nicole Grace
core   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

open access: yesAdvanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao   +6 more
wiley   +1 more source

Antibacterial Effect of Diclofenac Sodium on Enterococcus faecalis.

open access: yesFrontiers in Dentistry, 2013
Non-steroidal anti-inflammatory drugs (NSAIDs) have shown antibacterial activity in some recent studies. The aim of this study was to evaluate the antibacterial effect of diclofenac against Enterococcus faecalis (E.
Amin Salem-Milani   +6 more
doaj  

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