Results 61 to 70 of about 208,470 (355)

Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis. [PDF]

, 2017
AimTo evaluate the effects of metformin (Met) on inflammation, oxidative stress, and bone loss in a rat model of ligature-induced periodontitis.Materials & methodsMale albino Wistar rats were divided randomly into five groups of twenty-one rats each,
Araújo Júnior, Raimundo Fernandes de, Araújo, Aurigena Antunes de, Araújo, Lorena de Souza, Brito, Gerly Anne de Castro, Guedes, Paulo Marcos Matta, Hiyari, Sarah, Leitão, Renata Ferreira de Carvalho, Medeiros, Caroline Addison Carvalho Xavier de, Pereira, Aline de Sousa Barbosa Freitas, Pirih, Flávia Q   +9 more
core   +3 more sources

Cap‐oPMN: Oral Inflammatory Load Quantification Using Capillary Microfluidics and Automated Image Processing

Advanced Materials Technologies, EarlyView.
ABSTRACT Quantifying oral polymorphonuclear neutrophils (oPMNs) is a clinically validated approach for assessing periodontal inflammation. However, current methods, such as manual hemocytometry and flow cytometry, are time‐consuming (>3 h), require invasive sampling, and depend on staining and complex instrumentation, making them unsuitable for point ...
Mohsen Hassani, Azam Zare, Fatemeh Soheili, S. M. Mahdi H. Daneshvar, Mahdi Amrollahi Biouki, Yasaman Tahernezhad, Chunxiang Sun, Michael Glogauer, Ebrahim Ghafar‐Zadeh, Amir Sanati‐Nezhad   +9 more
wiley   +1 more source

Periodontitis as a potential risk factor for premature delivery

Journal of Mind and Medical Sciences, 2021
Pregnancy is a particular period of time for a woman, so that it is important to accurately determine the impact of adjacent pathologies on the natural evolution of the nine months of pregnancy.
Ana Turcu-Duminică, Anca Silvia Dumitriu, Stana Paunica, Corina Gică, Radu Botezatu, Nicolae Gică, Gheorghe Peltecu, Anca Maria Panaitescu   +7 more
doaj   +1 more source

Microbiota, Oral Microbiome, and Pancreatic Cancer [PDF]

, 2014
Only 30% of patients diagnosed with pancreatic cancer survive one year post-diagnosis. Progress in understanding the causes of pancreatic cancer has been made, including solidifying the associations with obesity and diabetes, and a proportion of cases ...
Izard, Jacques, Michaud, Dominique S.
core   +2 more sources

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Periodontal disease is associated with the risk of cardiovascular disease independent of sex: A meta-analysis

Frontiers in Cardiovascular Medicine, 2023
ObjectivesStudies have established a link between periodontal disease and cardiovascular disease (CVD), but it is unclear whether there is a sex difference in their association.MethodsThe PubMed, Embase, and Cochrane databases were searched until June ...
Yurong Leng, Yurong Leng, Yurong Leng, Qinwen Hu, Qin Ling, Xiongda Yao, Menglu Liu, Jiawei Chen, Zhiwei Yan, Qun Dai, Qun Dai, Qun Dai   +11 more
doaj   +1 more source

Microbial differences between dental plaque and historic dental calculus are related to oral biofilm maturation stage [PDF]

, 2019
Dental calculus, calcified oral plaque biofilm, contains microbial and host biomolecules that can be used to study historic microbiome communities and host responses.
CJ Adler, C Warinner, C Warinner, S Buckley, IM Velsko, J Hendy, ID Mandel, C Warinner, C Walker, V Zijnge, P Ramberg, D Belstrøm, PE Kolenbrander, WG Wade, SS Socransky, IM Velsko, SC Holt, M Umeda, BH Mullally, JW Lee, IM Velsko, LM Shaddox, AW Aruni, KL Cross, L Albayrak, S Yost, VM Barnes, JL Ebersole, S Yost, P Jorth, A Basic, RR Jersie-Christensen, T Imamura, LS Weyrich, AA Ribeiro, EL Gross, A Simón-Soro, Zachary D. Moye, O Manor, SM Dabdoub, D Belstrøm, RC Page, S Hillson, A Ogden, S Brooks, JL Buckberry, D Ferembach, CO Lovejoy, TW Phenice, LAF Frantz, P Skoglund, P Skoglund, M. Meyer, A Ginolhac, H Jónsson, A Peltzer, M Schubert, H Li, H Li, M Meyer, D Knights, N Segata, DT Truong, DH Parks, DH Parks, M Bastian, R Overbeek, DH Huson, MC Chambers, FE Dewhirst   +69 more
core   +4 more sources

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Black-pigmented anaerobic bacteria associated with ovine periodontitis [PDF]

, 2017
Periodontitis is a polymicrobial infectious disease that causes occlusion change, tooth loss, difficulty in rumination, and premature culling of animals.
Borsanelli, Ana C., Busin, Valentina, Dutra, Iveraldo S., Gaetti-Jardim, Elerson, Riggio, Marcello P., Schweitzer, Christiane M., Viora, Lorenzo   +6 more
core   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source