Results 81 to 90 of about 4,526,093 (336)

Comparison of the frequency of periodontal pathogenic species of diabetics and non‐diabetics and its relation to periodontitis severity, glycemic control and body mass index

open access: yesClinical and Experimental Dental Research, 2021
Objectives To investigate common pathogenic bacteria of periodontal diseases (PD) in patients with type 2 diabetes mellitus (T2DM) and its relationship with PD severity, glycemic control and body mass index (BMI).
Mojtaba Akherati   +3 more
doaj   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

open access: yesAdvanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck   +8 more
wiley   +1 more source

Microbiota, Oral Microbiome, and Pancreatic Cancer [PDF]

open access: yes, 2014
Only 30% of patients diagnosed with pancreatic cancer survive one year post-diagnosis. Progress in understanding the causes of pancreatic cancer has been made, including solidifying the associations with obesity and diabetes, and a proportion of cases ...
Izard, Jacques, Michaud, Dominique S.
core   +2 more sources

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

open access: yesAdvanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li   +9 more
wiley   +1 more source

Patterns of Oral Microbiota Diversity in Adults and Children: A Crowdsourced Population Study. [PDF]

open access: yes, 2020
Oral microbiome dysbiosis has been associated with various local and systemic human diseases such as dental caries, periodontal disease, obesity, and cardiovascular disease.
Burcham, Zachary M   +6 more
core  

Microbiota and chronic inflammatory arthritis. an interwoven link [PDF]

open access: yes, 2016
Background: Only recently, the scientific community gained insights on the importance of the intestinal resident flora for the host's health and disease.
D'Amelio, Raffaele   +3 more
core   +2 more sources

Dental Students’ Knowledge, Confidence, Ability, and Self-Reported Difficulties in Periodontal Education: A Mixed Method Pilot Study

open access: yesDentistry Journal, 2022
Evidence on periodontal education areas in which students have difficulties and their factors are limited. In this study, third- and fourth-year dental students’ knowledge was assessed as well as their confidence and ability in five periodontal ...
Amirsalar Mofidi   +8 more
doaj   +1 more source

Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity

open access: yesAdvanced Science, EarlyView.
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin   +19 more
wiley   +1 more source

A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease [PDF]

open access: yes, 2016
Periodontal disease is an inflammatory disease with high prevalence in adults that leads to destruction of the teeth-supporting tissues. Periodontal therapy has been traditionally directed at reduction of the bacterial load to a level that encourages ...
Battino, Maurizio   +4 more
core   +5 more sources

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman   +5 more
wiley   +1 more source

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