Effect of hypoestrogenism on the alveolar bone and periodontal ligament [PDF]
Background: Previous studies have shown that ovariectomy can alter bone structure, especially in the maxilla, as well as the periodontal ligament at the molecular level, and lead to cementum accumulation in the apical region.
Ronald De La Cruz-Rodriguez +4 more
doaj +2 more sources
A 3D Collagen–Alginate Hydrogel Model for Mechanoregulation of Autophagy in Periodontal Ligament Cells [PDF]
Mechanical loading is a central cue in periodontal tissues, where compression of the periodontal ligament guides remodeling and orthodontic tooth movement (OTM).
Xueping Kang +8 more
doaj +2 more sources
QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF-κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis. [PDF]
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Li H +9 more
europepmc +2 more sources
Periodontium regeneration and repair is a controversial and difficult point in the treatment of periodontosis. The proliferation, differentiation, migration and adhesion of periodontal ligament cells and the dynamic relationship between periodontal ...
LI Qi +3 more
doaj +1 more source
Significant type I and type III collagen production from human periodontal ligament fibroblasts in 3D peptide scaffolds without extra growth factors. [PDF]
We here report the development of two peptide scaffolds designed for periodontal ligament fibroblasts. The scaffolds consist of one of the pure self-assembling peptide scaffolds RADA16 through direct coupling to short biologically active motifs.
Yoshiyuki Kumada, Shuguang Zhang
doaj +1 more source
ILC1s and ILC3s Exhibit Inflammatory Phenotype in Periodontal Ligament of Periodontitis Patients
Innate lymphoid cells (ILCs) are emerging as important players in inflammatory diseases. The oral mucosal barrier harbors all ILC subsets, but how these cells regulate the immune responses in periodontal ligament tissue during periodontitis remains ...
Changyi Li +9 more
doaj +1 more source
Roles of extracellular adenosine triphosphate on the functions of periodontal ligament cells
Objective Adenosine triphosphate (ATP) is an essential nucleotide that is normally present in both intracellular and extracellular compartments. Extracellular ATP (eATP) has a pivotal role in both physiological and pathological processes of periodontal ...
Maythwe Kyawsoewin +5 more
doaj +1 more source
Background. Angiogenic tissue engineering is a vital problem waiting to be settled for periodontal regeneration. Erythropoietin, a multieffect cytokine, has been reported as a protective factor for cell fate.
Denghao Huang +5 more
doaj +1 more source
Human periodontal ligament-derived cells are important seed cells for periodontal regeneration, and their osteogenic potential closely affects alveolar bone repair and periodontal regeneration.
Albert Sufianov +6 more
doaj +1 more source
Activity of 25-hydroxylase in human gingival fibroblasts and periodontal ligament cells. [PDF]
We previously demonstrated that 25-hydroxyvitamin D(3) concentrations in gingival crevicular fluid are 300 times higher than those in the plasma of patients with aggressive periodontitis. Here we explored whether 25-hydroxyvitamin D(3) can be synthesized
Kaining Liu, Huanxin Meng, Jianxia Hou
doaj +1 more source

