Results 191 to 200 of about 248,788 (305)

EPLIN stabilizes cell-cell adhesion complexes to facilitate TGF-β1-induced fibroblastic differentiation of human periodontal ligament stem cells. [PDF]

Stem Cells
Choi AH, Ko SY, Jang YJ.
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Osteogenic differentiation of gingival and periodontal ligament fibroblasts inhibits osteoclast formation in 2D and 3D fibrin cultures. [PDF]

Bone Rep
Ceylan M, de Vries TJ, Runderkamp WJAM, Jansen IDC, Schimmel IM, Picavet-Havik DI, Laine ML, Schoenmaker T.   +7 more
europepmc   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

PTEN Inhibition Suppresses Differentiation in Periodontal Ligament Stem Cells. [PDF]

Int J Mol Sci
Phothichailert S, Nowwarote N, Kornsuthisopon C, Srithanyarat SS, Trachoo V, Namangkalakul W, Egusa H, Osathanon T.   +7 more
europepmc   +1 more source

Hydrogels in Periodontal and Craniofacial Regeneration: Current Applications and Next‐Generation Biomaterials

Journal of Periodontal Research, EarlyView.
Hydrogel‐based therapies have proven to be valuable tools to address the unique regeneration challenges of complex multi‐domain periodontal and craniofacial tissues. This review highlights and classifies clinically approved and emerging hydrogel therapies indicated for the regeneration of periodontal and craniofacial tissues.
Z. Gouveia, M. Diba, B. T. Yilmaz, Jae‐Kook Cha, D. T. Wu, D. J. Mooney   +5 more
wiley   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF-κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis. [PDF]

Adv Sci (Weinh)
Li H, Yang X, Wang H, Kuang Y, Hu Y, Li H, Li S, Zeng D, Li J, Song J.   +9 more
europepmc   +1 more source

30 Years of Enamel Matrix Derivative (EMD): Biological Foundations and Systematic Review With Meta‐Analyses Across Multiple Clinical Indications

Journal of Periodontal Research, EarlyView.
EMD is one of the few biological agents with human histologic evidence supporting periodontal regeneration. This is reflected in improved clinical outcomes when used in regenerative surgery for intrabony defects. Despite its biological plausibility for broader therapeutic applications, further high‐quality randomized clinical trials are needed to ...
Richard J. Miron, Nima Farshidfar, Yu‐Kang Tu, Chian‐Heng Su, Paras Ahmad, Nathan E. Estrin, Reinhard Gruber, Yoshinori Shirakata, Dieter D. Bosshardt, Mario Romandini, Anton Sculean   +10 more
wiley   +1 more source

Bioactivity and Regenerative Potential of Calcium Silicate-Based Endodontic Sealers on Human Periodontal Ligament Stem Cells: A Systematic Review of In Vitro Cellular Mechanisms. [PDF]

Cureus
Yaseen FI, Alribi AM, AlGhadyan YK, Alshehri NA, Alanazi TM, Aldhafeeri AS, Alyousef MS, Elkherayef SS, Albarqi AA, Alqahtani AM, Falatah AM.   +10 more
europepmc   +1 more source

Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications

Journal of Periodontal Research, EarlyView.
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu, Yuan Chen, Mario Romandini, Håvard Jostein Haugen, Sašo Ivanovski   +4 more
wiley   +1 more source