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Immunomodulatory properties of human periodontal ligament stem cells
Journal of Cellular Physiology, 2009AbstractTissue engineering utilizing periodontal ligament stem cells (PDLSCs) has recently been proposed for the development of new periodontal regenerative therapies. Although the use of autologous PDLSC transplantation eliminates the potential of a significant host immune response against the donor cells, it is often difficult to generate enough ...
Wada, N. +4 more
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Near Infrared Laser Photobiomodulation of Periodontal Ligament Stem Cells.
The Chinese journal of dental research, 2022To determine the effect of different energy densities of near infrared diode lasers with wavelengths of 810 or 940 nm on the proliferation and survival of periodontal ligament derived stem cells (PDLSCs).After isolation and characterisation, PDLSCs were cultured in clear 96-well plates.
Mohammd Ayyoub, Rigi-Ladez +4 more
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Recovery of Stem Cells from Cryopreserved Periodontal Ligament
Journal of Dental Research, 2005Human post-natal stem cells possess a great potential to be utilized in stem-cell-mediated clinical therapies and tissue engineering. It is not known whether cryopreserved human tissues contain functional post-natal stem cells. In this study, we utilized human periodontal ligament to test the hypothesis that cryopreserved human periodontal ligament ...
B. SEO +5 more
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Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium
Stem Cells and Development, 2019Periodontium is consisted of root cementum, bone lining the tooth socket, gingiva facing the tooth, and periodontal ligament (PDL). Its primary functions are support of the tooth and protection of tooth, nerve, and blood vessels from injury by mechanical loading.
Atsushi, Tomokiyo +2 more
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Periodontal ligament stem cells promote polarization of M2 macrophages
Journal of Leukocyte Biology, 2022AbstractMacrophages are widely distributed in a variety of tissues, and the different state of macrophages polarization is closely related to the occurrence, development, and prognosis of inflammation, including periodontitis, a chronic inflammatory disease leading to tooth loss worldwide.
Jiani, Liu +6 more
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Periodontal ligament stem cells: an update and perspectives
Journal of Investigative and Clinical Dentistry, 2014AbstractChronic periodontitis is a serious infectious and inflammatory oral disease of humans worldwide. Conventional treatment modalities are effective for controlling periodontal disease. However, the regeneration of damaged periodontal tissues remains a major challenge in clinical practice due to the complex structure of the periodontium.
Chamila Prageeth Pandula, PK +3 more
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Stem Cells and Development, 2018
The periodontal ligament (PDL) plays an important role in anchoring teeth in the bone socket. Damage to the PDL, such as after severe inflammation, can be treated with a therapeutic strategy that uses stem cells derived from PDL tissue (PDLSCs), a strategy that has received intense scrutiny over the past decade. However, there is an insufficient number
Sayuri, Hamano +8 more
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The periodontal ligament (PDL) plays an important role in anchoring teeth in the bone socket. Damage to the PDL, such as after severe inflammation, can be treated with a therapeutic strategy that uses stem cells derived from PDL tissue (PDLSCs), a strategy that has received intense scrutiny over the past decade. However, there is an insufficient number
Sayuri, Hamano +8 more
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Plasticity of Stem Cells Derived from Adult Periodontal Ligament
Regenerative Medicine, 2009The neural crest contains pluripotent cells that can give rise to neurons and glial cells of the peripheral nervous system, endocrine cells, connective tissue cells, muscle cells and pigment cells during embryonic development. Stem cells derived from the neural crest may still reside in neural crest derivatives including the periodontal ligament (PDL).
C-Y Charles, Huang +5 more
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Location of putative stem cells in human periodontal ligament
Journal of Periodontal Research, 2006Background and Objective: The origin of cells in the mature periodontium, and the location of their progenitors, are still unknown. It is also unknown whether inflammation influences the number and distribution of these cells within the periodontium. Molecules such as STRO‐1, CD146 and CD44 have been identified on a variety of mesenchymal stem cells ...
Chen, S. +3 more
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Xeno-Free Culture of Human Periodontal Ligament Stem Cells
2014The possibility of transplanting adult stem cells into damaged organs has opened a new prospective for the treatment of several human pathologies. Currently, in vitro expansion and culture of mesenchymal stem cells is founded on supplementing cell culture and differentiation medium with fetal calf serum (FCS) or fetal bovine serum (FBS) that contain ...
TRUBIANI, Oriana, DIOMEDE, FRANCESCA
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