Results 41 to 50 of about 25,953 (300)

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

open access: yesAdvanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li   +9 more
wiley   +1 more source

Mucogingival surgery with SureDerm application for gingival recession treatment in periodontics clinic University of Airlangga in 2022 [PDF]

open access: yes, 2022
Background: Gingival recession has become a serious problem since it has a high prevalence among the 88% population of the world. Various mucogingival therapy becomes treatment of choice for gingival recession, such as sub ephitelial connective tissue ...
Shafira Kurnia, -, Lubna, -, Mulyati, -
core   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia   +10 more
wiley   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

open access: yesAdvanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun   +15 more
wiley   +1 more source

Protease‐Triggered Chromogenic Release From Peptide‐Modified Calcium Carbonate Microspheres Enables Colorimetric Detection of Porphyromonas gingivalis Activity

open access: yesAdvanced Science, EarlyView.
We report a chromogenic release‐based assay system with protease‐cleavage peptide‐modified calcium carbonate microspheres for colorimetric detection of Porphyromonas (P.) gingivalis activity. In response to Arg‐specific gingipain secreted by P. gingivalis, the supernatant becomes colored, enabling colorimetric analysis and providing the monitoring of ...
Yuki Hiruta   +9 more
wiley   +1 more source

Association between periodontitis and lung disease [PDF]

open access: yesRGO: Revista Gaúcha de Odontologia, 2010
Objective: To verify the association between periodontal disease and lung disease from an epidemiological, case and control survey, in patients who attended the first aid service of the Adriano Jorge Foundation Hospital, Manaus, Amazonas, Brazil, from ...
Fabiano Rito Macedo   +4 more
doaj  

Phytotherapy in periodontics

open access: yes, 2020
Periodontal diseases continue to be the most commonly occurring oral diseases in modern times. Plaque-induced gingivitis and periodontitis are caused by the penetration of pathogens from the bacterial plaque into the connective tissue, resulting in an ...
dos Reis-Prado, Alexandre Henrique   +6 more
core  

Interest in pursuing the specialty of periodontology: a perspective from pre-doctoral periodontal directors and periodontics residents [PDF]

open access: yes, 2010
Interest in periodontics as a career by dental students remains low compared to other dental clinical specialties. The purpose of this research is to report the perceived value of periodontal education and general enthusiasm toward periodontics ...
Lewis, Imani Edward
core   +1 more source

A Roadmap towards Precision Periodontics

open access: yes, 2021
Periodontitis is among the most common health conditions and represents a major public health issue related to increasing prevalence and seriously negative socioeconomic impacts.
Danilo Vojvodic   +3 more
core   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

open access: yesAdvanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu   +12 more
wiley   +1 more source

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