Results 91 to 100 of about 179,362 (317)

Dentofacial Malocclusion in Neurofibromatosis 1 in Finland

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Neurofibromatosis 1 (NF1) is an inherited disease that can be accompanied by oral health problems such as caries, periodontitis, and tumors affecting the oral cavity. Also, different maxillary and mandibular malformations are associated with NF1.
Vivian Reinhold, Mikko Valtanen, Kari Auranen, Stina Syrjänen, Sirkku Peltonen, Juha Peltonen, Roope A. Kallionpää   +6 more
wiley   +1 more source

Detection of Exosomal PD-L1 RNA in Saliva of Patients With Periodontitis

Frontiers in Genetics, 2019
Periodontitis is the most prevalent inflammatory disease of the periodontium, and is related to oral and systemic health. Exosomes are emerging as non-invasive biomarker for liquid biopsy. We here evaluated the levels of programmed death-ligand 1 (PD-L1)
Jialiang Yu, Yusheng Lin, Xiao Xiong, Kai Li, Zhimeng Yao, Hongmei Dong, Hongmei Dong, Zuojie Jiang, Dan Yu, Sai-Ching Jim Yeung, Sai-Ching Jim Yeung, Hao Zhang, Hao Zhang   +12 more
doaj   +1 more source

Would You Recognize Lupus? [PDF]

, 2018
Systemic Lupus Erythematosus, or SLE, is a chronic autoimmune disease which significantly affects various organs of the body and the oral cavity. According to various studies, SLE can cause an increased risk of periodontitis, fungal infections, and ...
Brown, Barbara, Simms, Maegan, Smith, Sydney C   +2 more
core   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

Advanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu, Xu Changzhi, Deng Qiong, Liang Hui   +3 more
wiley   +1 more source

Hepatitis B infection is associated with periodontitis: the national health and nutrition examination survey (2009–2014)

BMC Oral Health
Background Current research has been inconclusive regarding whether hepatitis B infection is associated with an increased risk of periodontitis. This study aims to test the null hypothesis that no association exists between hepatitis B infection and an ...
XianRun Chen, Jukun Song, JiangLing Sun, JiQin Zhang, XingJin Chen, ChongWen Zeng, JiaXin Hu, XingTao Chang, FuQian Jin, SiYang Luo, Zhu Chen, Yi Luo   +11 more
doaj   +1 more source

Periodontitis in patients with cirrhosis: a cross-sectional study

BMC Oral Health, 2018
Background Many patients with cirrhosis have poor oral health but little is known on periodontitis, and its clinical significance is largely unknown. This study aimed to examine the prevalence and predictors of periodontitis, and evaluate the association
Lea Ladegaard Grønkjær, Palle Holmstrup, Søren Schou, Johanne Kongstad, Peter Jepsen, Hendrik Vilstrup   +5 more
doaj   +1 more source

Influence of inflammation on bleeding and wound healing following surgical extraction of impacted lower third molars

BMC Oral Health, 2023
Objective This study aimed to investigate the effect of inflammatory states following impacted lower third molar (ILTM) surgery regarding postoperative bleeding and wound healing.
Yusheng Cheng, Maged Ali Al-Aroomi, Naseem Ali Al-Worafi, Essam Ahmed Al‑Moraissi, Changfu Sun   +4 more
doaj   +1 more source

Study on porphyromonas gingivalis- and porphyromonas endodontalis- mediated signaling pathway [PDF]

, 2019
It is known that anaerobic microbes like Porphyromonas gingivalis (P. gingivalis) are involved in the progression and initiation of multiple forms of periodontal disease such as chronic periodontitis.
Alamry, Nujud
core  

Oral Inflammation, Tooth Loss, Risk Factors, and Association with Progression of Alzheimer’s Disease [PDF]

, 2014
Periodontitis is a polymicrobial chronic inflammatory disease of tooth-supporting tissues with bacterial etiology affecting all age groups, becoming chronic in a subgroup of older individuals.
Crean, Stjohn, Harding, Alice, Kesavalu, Lakshmyya, Robinson, Sarita Jane, Simmons, Tal, Singhrao, Simarjit Kaur   +5 more
core   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang, Chao Yu, Mengyue Hu, Lu Wang, Meixia Chen, Hanmo Liu, Nan Wu, Jie Hou   +7 more
wiley   +1 more source