Results 111 to 120 of about 190,069 (364)

Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects

Animal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang, Yiming Liu, Dan Chen, Leiming Liu, Leimin Sun, Lingling Zhang   +5 more
wiley   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

Advanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu, Xu Changzhi, Deng Qiong, Liang Hui   +3 more
wiley   +1 more source

Development, Evaluation, and Characterization of a Novel Mucoadhesive Film Containing Pterodon pubescens Benth Ethanolic Extract for Dental Use

Journal of Applied Polymer Science, EarlyView.
Pterodon pubescens Mucoadhesive Film for dental use. ABSTRACT Periodontal diseases involve infectious and inflammatory processes that affect oral tissues. Extracts from Pterodon pubescens Benth (sucupira) have demonstrated antinociceptive, anti‐inflammatory, anti‐edematogenic, and antiplatelet effects, highlighting their therapeutic potential for ...
Mariana Cecchetto Figueiredo, Fabiana Volpe Zanutto, Akmal Sabri, Tuany Zambroti Cândido, Leila Servat Medina, Ilza Maria de Oliveira Sousa, Rosanna Tarkany Basting, Lucia Elaine de Oliveira Braga, Ellen Cristina Souza de Oliveira, Simone Nataly Busato de Feiria, Bruno da Fonseca‐Santos, Marlus Chorilli, Ramiro Mendonça Murata, Mary Ann Foglio   +13 more
wiley   +1 more source

Alterations and correlations in dental plaque microbial communities and metabolome characteristics in patients with caries, periodontitis, and comorbid diseases

BMC Oral Health
Backgrounds The pathogenic microorganisms and clinical manifestations of caries and periodontitis are different, caries and periodontitis are usually discussed separately, and the relationship between them is ignored. Clinically, patients prone to dental
Ying Wang, Fei Yang, Yuan Wang, Shuli Deng, Rui Zhu   +4 more
doaj   +1 more source

Microbial risk factors of cardiovascular and cerebrovascular diseases: potential therapeutic options [PDF]

, 2008
Infection and inflammation may have a crucial role in the pathogenesis of atherosclerosis. This hypothesis is supported by an increasing number of reports on the interaction between chronic infection, inflammation, and atherogenesis.
Abbas, M.A., Comi, G, Corea, F, Fawi, G, Galantucci, S, Guenther, A, Kwan, Joseph W.   +6 more
core   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

The Antimicrobial Effect of Silver Ion Impregnation into Endodontic Sealer against Streptococcus mutans. [PDF]

, 2008
Pulpal and periradicular diseases are primarily caused by bacterial invasion of the root canal system as a result of caries progression. The presence of residual bacteria at the time of root canal completion (obturation) is associated with significantly ...
Chugal, N, Hsiao, G, Kang, MK, Kim, D, Kreth, J, Mito, R, Nguyen, M, Shi, W   +7 more
core   +3 more sources

Periodontal vaccine

Indian Journal of Dental Research, 2011
Vaccine is the name applied generally to a substance of the nature of dead or attenuated living infectious material introduced into the body with the object of increasing its power to resist or get rid of a disease. Vaccines are generally prophylactic, i.e. they ameliorate the effects of future infection.
Ranjan Malhotra, Anoop Kapoor, Vishakha Grover, Aaswin Kaur Tuli   +3 more
openaire   +3 more sources

In situ biomimetic materials for dentin repair

BMEMat, EarlyView.
This review primarily discusses the role and clinical application of key biomimetic materials for in situ dentin repair, providing a feasible foundation for future material and performance optimization in situ dentin regeneration. Abstract Dental defects, ranking among the most prevalent diseases globally, pose a serious threat to human health, with ...
Jingjing Deng, Siyi Ren, Xuliang Deng, Yan Wei   +3 more
wiley   +1 more source

Single-Cell Enumeration of an Uncultivated TM7 Subgroup in the [PDF]

, 2003
Specific oligonucleotide hybridization conditions were established for single-cell enumeration of uncultivated TM7 and IO25 bacteria by using clones expressing heterologous 16S rRNA. In situ analysis of human subgingival crevice specimens revealed that a
Armitage, Gary C., Ouverney, Cleber C., Relman, David A.   +2 more
core   +1 more source