Results 211 to 220 of about 268,429 (399)

Design characteristics of studies evaluating the effect of non‐surgical periodontal treatment on systemic health outcomes

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Evidence for whether and how non‐surgical periodontal treatment (NSPT) improves systemic outcomes remains equivocal. Inconclusive findings may in part be due to design variations of randomized controlled trials (RCTs) in this field.
Timothy Treat   +6 more
wiley   +1 more source

Dose‐dependent association of systemic comorbidities with periodontitis severity: A large population cross‐sectional study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background To examine whether the associations between periodontitis and multiple systemic conditions increase with increasing severity of periodontitis using a multi‐center electronic health record (EHR) repository. Methods A cross‐sectional analysis was conducted using EHR data from 9 dental schools in the United States.
Muhammad H. A. Saleh, Hamoun Sabri
wiley   +1 more source

High-Dimensional Graphical Model Search with the gRapHD R Package [PDF]

open access: yes
This paper presents the R package gRapHD for efficient selection of high-dimensional undirected graphical models. The package provides tools for selecting trees, forests, and decomposable models minimizing information criteria such as AIC or BIC, and for
David Edwards   +2 more
core   +1 more source

Diversity and random forest models of oral microbiomes in periodontal health using publicly available data

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Evidence on the 16S metabarcoding of supragingival, subgingival, and salivary microbiomes in periodontal health remains limited. We aimed to analyze the diversity and potential of machine‐learning models of supragingival, subgingival, and salivary microbiomes in periodontal health. Methods A total of 848 samples (supragingival = 210;
Alba Regueira‐Iglesias   +6 more
wiley   +1 more source

Peri‐implant hypoxia as a potential barrier against ferroptotic mechanisms during peri‐implant diseases: A cross‐sectional study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Hypoxia modulates inflammation and oxidative stress through hypoxia‐inducible factor‐1α (HIF‐1α). Ferroptosis, an iron‐dependent cell death process, is regulated by glutathione peroxidase‐4 (GPX4) and involves lipid peroxidation markers like malondialdehyde (MDA).
Büşra Yılmaz   +5 more
wiley   +1 more source

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