Results 241 to 250 of about 104,154 (316)

Peri‐Implant Crevicular Fluid Analysis by Mid‐Infrared Spectroscopy in Peri‐Implantitis—A Pilot Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This study aimed to assess biochemical differences in peri‐implant crevicular fluid (PICF) using ATR‐FTIR spectroscopy and multivariate analysis, through a between‐participant comparison of healthy and peri‐implantitis (PI) sites, and a within‐participant comparison of PI‐PICF and GCF from contralateral periodontal healthy teeth ...
Francisco Maligno, Ricardo N. M. J. Páscoa, Pedro S. Gomes   +2 more
wiley   +1 more source

Lactylation-related gene signatures define immune heterogeneity and provide diagnostic biomarkers for periodontitis. [PDF]

Sci Rep
Zhu Y, Zhang X, Wei L, Bai Y, Wang T, Guo Y, Chen M, Jia S, Zhang X.   +8 more
europepmc   +1 more source

One‐Year Analysis of Clinical and Radiological Outcomes of Two‐Piece Zirconia Compared to Titanium Implants: A Multicenter Prospective Randomized Clinical Trial

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate the clinical performance of two‐piece zirconia implants with screw‐retained abutments compared to titanium implants after 1 year of loading. Materials and Methods In this multicenter, prospective, randomized clinical trial, 61 two‐piece zirconia and 61 titanium implants were placed and restored with single crowns ...
Marc Balmer, Michael Payer, Anke Steinwender, Valentin Herber, Ronald E. Jung, Sebastian Kühl   +5 more
wiley   +1 more source

Causal Gene Identification and Biomarker Prioritization in Periodontitis via Integrative Multiomics and Mendelian Randomization. [PDF]

Mediators Inflamm
Mo H, Chen L, Ren S, Wu Y, Tian A.
europepmc   +1 more source

Nanosilicates Enhanced Periodontal Angiogenesis by Regulating Microtubule Dynamic‐Mediated STAT3 Pathway

Cell Proliferation, EarlyView.
Nanosilicates triggered MAP4‐dependent microtubule remodelling via the ROS/MAPK pathway, shifting microtubules into a dynamic active state, which subsequently promoted activation of the STAT3 pathway, ultimately facilitating periodontal angiogenesis.
Lingling Shang, Yuhan Hu, Shaohua Ge
wiley   +1 more source

Effects of initial periodontal treatment on heat shock protein 90 and Interleukin-1β levels in gingival crevicular fluid of stage III periodontitis patients. [PDF]

BMC Oral Health
Caliskan N, Toker H, Celik AB, Guler OS, Al M, Tutar Y.   +5 more
europepmc   +1 more source

Alternative Polyadenylation Drives Runaway Pro‐Inflammatory Macrophages in Periodontitis by Enabling Escape From miRNA Repression

Cell Proliferation, EarlyView.
APA‐Guided Therapeutic miRNA Selection for Periodontitis. ABSTRACT Periodontitis is a chronic inflammatory disease driven by a dysregulated host immune response, in which macrophage‐mediated inflammation shifts from protective to pathological. While monocyte‐derived macrophages (MDMs) are known to adopt a destructive, M1‐like pro‐inflammatory phenotype,
Jing Zhang, Yilong Zhao, Jiaru Deng, Shuyuan Qu, Yiyi Zhou, Qin Zhao, Yufeng Zhang   +6 more
wiley   +1 more source

Effectiveness of local Tocilizumab administration in mitigating alveolar bone loss and inflammation in experimental periodontitis. [PDF]

Sci Rep
Martins AA, Lima MLS, Vieira GHA, Costa HES, Leitão RFC, Ribeiro SB, Medeiros CACX, Silva DNA, Suksakulchai R, Pirih FQ, Brito GAC, Garcia VB, Araújo Júnior RF, Lins RDAU, Araújo AA.   +14 more
europepmc   +1 more source

Hypoxia Exacerbates Periapical Periodontitis‐Associated Pathological Bone Loss via the Hypoxia‐Inducible Factor‐2α‐Calmodulin‐Dependent Protein Kinase IV Axis

Cell Proliferation, EarlyView.
Hypoxia exposure activates HIF‐2α, which binds to the Camk4 promoter to enhance RANKL‐mediated osteoclast differentiation, leading to aggravated alveolar bone resorption in periapical periodontitis. ABSTRACT Periapical periodontitis is one of the most common inflammatory bone destructive diseases. Epidemiological evidence suggests that hypoxia exposure,
Kang Gao, Yifan Xu, Haoran Du, Zixiao Li, Xiaochen Fang, Minghui Wang, Jia Liu, Xu Zha, Xianglong Han, Weihua Guo, Xicheng Liu, Jian Zhou   +11 more
wiley   +1 more source