Abstract Background Epithelium is the periodontal first line of defense against microbes. Discoidin domain receptor 1 (DDR1) is a collagen receptor expressed in epithelium. Ddr1 knockout (Ddr1−/−) mice develop periodontitis‐like defects, including junctional epithelium (JE) downgrowth, bacterial invasion, and alveolar bone loss.
Christina Zachariadou +3 more
wiley +1 more source
Investigating the genetic causality between periodontitis and intracranial aneurysms: A 2-sample Mendelian randomization study. [PDF]
Chen Y, Huang J, Zhou Q, Kang Y.
europepmc +1 more source
The influence of flap design on the relevance of biomaterials in regenerative periodontal surgery
Abstract Background The aim of this systematic review was to explore whether the benefits of biomaterials in periodontal regenerative/reconstructive surgery are affected by the type of flap employed. The study addresses the existing gap in the evidence to substantiate the beneficial effect of minimal invasive periodontal surgical approach compared to a
Payvand Menhadji +2 more
wiley +1 more source
Causal effects of gut microbiota on periodontitis risk: a meta-analysis of Mendelian randomization studies. [PDF]
Yu J, Zuo Y, Yang L, Xu Q.
europepmc +1 more source
Additional file 8: of Epigenetic findings in periodontitis in UK twins: a cross-sectional study
Yuko Kurushima +11 more
openalex +1 more source
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
Multi-dimensional role of AGEs in periodontitis: from matrix remodeling to neuro-immune crosstalk. [PDF]
Dong YL, Lin H, Wen T, Guo ZL.
europepmc +1 more source
ABSTRACT Sepsis‐associated liver injury (SALI) plays a major role in aggravating disease progression and worsening prognosis in patients with sepsis. Macrophage polarization is a key factor in the modulation of SALI progression. Recent studies have shown that human breast milk‐derived exosomes (HBM‐Exos) regulate processes involved in macrophage ...
Zhao‐Bin Yang +3 more
wiley +1 more source
Association of torque teno virus in periodontitis: a systematic review, meta-analysis, and trial sequential analysis. [PDF]
Chauca-Bajaña L +10 more
europepmc +1 more source

