Results 31 to 40 of about 104,154 (316)

The impact of chronic periodontitis on serum tumor necrosis factor-α and HbA1c levels in type 2 diabetic patients

Saudi Journal for Health Sciences, 2021
Background: Diabetic patients are subject to chronic periodontitis which could adversely affect glycemic control. Aim: This study determined the impact of chronic periodontitis in patients with diabetes mellitus type 2 (DM 2).
Rehab Abdallah Abdalrahman, Bakri Gobara Gismalla   +1 more
doaj   +1 more source

NUMBER OF BLACK-PIGMENTED ANAEROBIC BACTERIA CONTAINED IN THE GINGIVAL CREVICULAR FLUID (GCF) OF PATIENTS SUFFERING FROM THE CHRONIC PERIODONTITIS AND AGGRESSIVE PERIODONTITIS

ODONTO: Dental Journal, 2021
Background: Chronic Periodontitis (CP) and Aggressive Periodontitis (AP) are chronic inflammation diseases in the dental supporting tissues characterized by the existence of pocket inside, alveolar bone attachments and damages rapidly leading to the ...
Depi Praharani, Peni Pujiastuti, Melok Aris Wahyukundari, Yuliana Mahdiyah Daat Arina, Desi Sandra Sari   +4 more
doaj   +1 more source

The salivary metabolomics analyses reveal the variable metabolites in distinct staging of periodontitis

BMC Oral Health
Objective Saliva, which is a critical component of the oral ecosystem, undergoes dynamic changes, particularly during the onset and progression of periodontitis.
Lijun Wang, Wen Lu, Wei Ju, Wenxin Yao, Chaowen Shi, Xihu Yang, Wenhao Qian   +6 more
doaj   +1 more source

DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption

Advanced Functional Materials, EarlyView.
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim, Dai‐Hwan Kim, Priyannth R. Sundharbaabu, Chae Yeon Lee, Jina Bae, Jiyu Hyun, Young‐Ju Jang, Haeni Kim, Min‐Ho Hong, Juewen Liu, Tobias Fey, Suk Ho Bhang, Jun Hyuk Heo, Jung Heon Lee   +13 more
wiley   +1 more source

LINC00342 regulates the PI3K-AKT signaling pathway via the miR-149-5p/FGF11 axis and affects the progression of oral cancer

Discover Oncology
Background A large number of long non-coding RNAs (lncRNAs) have been implicated in the progression of oral cancer (OC). This study aimed to investigate the role of a novel lncRNA, LINC00342, in OC and elucidate its molecular mechanism.
Yimiao Chen, Yanchun Wang, Wenbo Zhang
doaj   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

Periodontal maintenance [PDF]

Australian Dental Journal, 2009
AbstractThe main goal of periodontal therapy is to establish an oral environment compatible with periodontal health by the physical disruption of the plaque biofilm and adjunctive chemical means if required. Implicit in this objective is the ongoing requirement of detection and interception of new and recurrent disease, which continues at selected ...
openaire   +2 more sources

Integrated Flexible Zwitterionic Electrochemical Sensor Platform for Real‐Time Salivary Glucose Quantification

Advanced Sensor Research, EarlyView.
A flexible electrochemical sensor platform can enable continuous, real‐time monitoring of salivary glucose for applications confined to spaces such as the oral cavity. Surface modifications with Prussian blue, chitosan, and zwitterionic polymers enhance sensitivity, selectivity, and antiadherent performance.
Stephanie Klinghammer, Gylxhane Kastrati, Leif Riemenschneider, Michael Geiger‐Hoffmann, Luis Antonio Panes‐Ruiz, Johan Peter Woelber, Christian Hannig, Gianaurelio Cuniberti, Torsten Sterzenbach   +8 more
wiley   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

Obesity correlated to a higher risk of acquiring periodontitis: a cross-sectional study [version 2; peer review: 2 approved]

F1000Research, 2022
Background: The present study aimed to investigate the correlation between obesity and periodontitis, among other risk factors for periodontitis.   Methods:  In total, 262 Indonesian male and female subjects were analysed for body mass index (BMI), oral ...
Lindawati S. Kusdhany, Nurtami Soedarsono, Sri Lelyati C. Masulili, Chaerita Maulani, Elza Ibrahim Auerkari, Chiquita Prahasanti   +5 more
doaj   +1 more source