Results 91 to 100 of about 485,635 (374)

Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
Nonalcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation and extracellular matrix stiffening. An in vitro NAFLD model is developed using engineered hydrogels (G′ ≈ 1–6 kPa) and iPSC‐derived hepatic organoids. It is demonstrated that higher stiffness can increase lipid droplet accumulation, fibrosis, and metabolic dysregulation ...
Yueming Liu, Aidan E. Gilchrist, Patrik K. Johansson, Yuan Guan, Jaydon D. Deras, Yu‐Chung Liu, Sofia Ceva, Michelle S. Huang, Renato S. Navarro, Annika Enejder, Gary Peltz, Sarah C. Heilshorn   +11 more
wiley   +1 more source

Perioperative/postoperative anxiety and its interventions in gynecological cancers: a comprehensive review of clinical evidence

Frontiers in Psychiatry
Gynecological cancers are prevalent malignancies among females, and surgical intervention is the primary therapeutic approach offering the possibility of a definitive cure.
Beibei Chen, Chunyan Chen, Xiumin Zhao, Xiaoxia Wu   +3 more
doaj   +1 more source

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults.

Cochrane Database of Systematic Reviews, 2018
BACKGROUND The management of postoperative pain and recovery is still unsatisfactory in a number of cases in clinical practice. Opioids used for postoperative analgesia are frequently associated with adverse effects, including nausea and constipation ...
S. Weibel, Y. Jelting, N. Pace, A. Helf, L. Eberhart, K. Hahnenkamp, M. Hollmann, D. Poepping, A. Schnabel, P. Kranke   +9 more
semanticscholar   +1 more source

Photo‐Biomodulation of the Hippocampus Using Near‐Infrared Laser to Enhance Cognitive Function in Mice

Advanced Science, EarlyView.
Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan, Han‐Wen Gu, Yan‐Bo Zhou, Sophie Ma, Daqing Ma, Pan‐Miao Liu, Jian‐Jun Yang   +6 more
wiley   +1 more source

The role of immunotherapy in early-stage and metastatic NSCLC

Pathology and Oncology Research
In the past decade we have seen new advances and thus remarkable progress in the therapeutic options for non-small cell lung cancer (NSCLC). Among cytostatic therapies with new approaches in molecularly targeted therapies, we see new developments in a ...
Attila Lieber, Attila Makai, Zsuzsanna Orosz, Tamás Kardos, Susil Joe Isaac, Ilona Tornyi, Nóra Bittner   +6 more
doaj   +1 more source

Perioperative intravenous ketamine for acute postoperative pain in adults.

Cochrane Database of Systematic Reviews, 2018
BACKGROUND Inadequate pain management after surgery increases the risk of postoperative complications and may predispose for chronic postsurgical pain.
E. Brinck, E. Tiippana, M. Heesen, R. Bell, S. Straube, R. Moore, V. Kontinen   +6 more
semanticscholar   +1 more source

Injectable and Sprayable Thermoresponsive Hydrogel with Fouling‐Resistance as an Effective Barrier to Prevent Postoperative Cardiac Adhesions

Advanced Science, EarlyView.
Postoperative cardiac adhesions lead to numerous difficulties in reoperation procedures. Here, a thermo‐responsive in situ formed hydrogel is shown to can reliably cover the wounds after a convenient spraying or injection and significantly reduce adhesion formation in primary and recurrent cardiac injury adhesion models.
Kun Shi, Tao Li, Xulin Hu, Wen Chen, Yan Yu, Zhongwu Bei, Liping Yuan, Qi Tong, Jiafeng Liu, Qiang Fan, Yongjun Qian, Zhiyong Qian   +11 more
wiley   +1 more source

Management of Non-Metastatic Non-Small Cell Lung Cancer (NSCLC) with Driver Gene Alterations: An Evolving Scenario

Current Oncology
The ever-growing knowledge regarding NSCLC molecular biology has brought innovative therapies into clinical practice; however, the treatment situation in the non-metastatic setting is rapidly evolving. Indeed, immunotherapy-based perioperative treatments
Valeria Fuorivia, Ilaria Attili, Carla Corvaja, Riccardo Asnaghi, Ambra Carnevale Schianca, Pamela Trillo Aliaga, Ester Del Signore, Gianluca Spitaleri, Antonio Passaro, Filippo de Marinis   +9 more
doaj   +1 more source

Perioperative Morbidity and Mortality of Patients With COVID-19 Who Undergo Urgent and Emergent Surgical Procedures

Annals of Surgery, 2020
Supplemental Digital Content is available in the text Objective: To evaluate the perioperative morbidity and mortality of patients with COVID-19 who undergo urgent and emergent surgery.
A. Knisely, Z. Zhou, Jenny Wu, Yongmei Huang, K. Holcomb, A. Melamed, A. Advincula, Anil K Lalwani, F. Khoury‐Collado, A. Tergas, C. S. St. Clair, J. Hou, D. Hershman, M. D'alton, Y. Huang, J. Wright   +15 more
semanticscholar   +1 more source

Hydrolyzable Bio‐Based Bisphenols Enabled by the Tishchenko Reaction for Polyurethane Vitrimers with Closed‐Loop Recyclability

Advanced Science, EarlyView.
This study employs the Tishchenko coupling reaction to obtain bio‐based bisphenols containing degradable ester bonds with 100% atom utilization. Based on these bio‐based bisphenols, a fully bio‐based polyurethane Covalent Adaptable Networks are constructed, while simultaneously endowing the material with closed‐loop recyclability, degradability, and ...
Jiewen Wang, Hongru Qiang, Rong Huang, Dan Zhao, Zihan Tong, Zhen Fan, Jianzhong Du, Yunqing Zhu   +7 more
wiley   +1 more source