Results 111 to 120 of about 697,428 (396)

A systematic review of therapeutic interventions to reduce acute and chronic post-surgical pain after amputation, thoracotomy or mastectomy [PDF]

, 2014
BACKGROUND: Perioperative neuropathic pain is under-recognized and often undertreated. Chronic pain may develop after any routine surgery, but it can have a far greater incidence after amputation, thoracotomy or mastectomy.
Ibarra M.M., Macintyre P.E., Mendola C., Woolf C.J.   +3 more
core   +1 more source

Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation.

New England Journal of Medicine, 2015
BACKGROUND It is uncertain whether bridging anticoagulation is necessary for patients with atrial fibrillation who need an interruption in warfarin treatment for an elective operation or other elective invasive procedure.
J. Douketis, A. Spyropoulos, S. Kaatz, R. Becker, J. Caprini, A. Dunn, D. Garcia, A. Jacobson, A. Jaffer, D. Kong, S. Schulman, A. Turpie, V. Hasselblad, T. Ortel   +13 more
semanticscholar   +1 more source

Perioperative Acute Kidney Injury.

Anesthesiology, 2020
Perioperative organ injury is among the leading causes of morbidity and mortality of surgical patients. Among different types of perioperative organ injury, acute kidney injury occurs particularly frequently and has an exceptionally detrimental effect on
Sam D Gumbert, F. Kork, M. Jackson, N. Vanga, Semhar J. Ghebremichael, Christy Wang, H. Eltzschig   +6 more
semanticscholar   +1 more source

Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy

Advanced Science, EarlyView.
This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang, Xue Jiang, Bingrui Xiong, Jiayi Chen, Xin Liu, Siyuan Wang, Bofu Li, Mian Peng, Wei Li   +8 more
wiley   +1 more source

Cefazolin Prophylaxis for Total Joint Arthroplasty: Obese Patients Are Frequently Underdosed and at Increased Risk of Periprosthetic Joint Infection [PDF]

, 2018
Background One of the most effective prophylactic strategies against periprosthetic joint infection (PJI) is administration of perioperative antibiotics. Many orthopedic surgeons are unaware of the weight-based dosing protocol for cefazolin.
Greenky, Max R., Kheir, Michael M., Parvisi, Javad, Rondon, Alexander J., Shohat, Noam, Tan, Timothy L.   +5 more
core   +1 more source

Near‐Infrared Afterglow Imaging‐Guided Surgical Resection and Synergistic Photodynamic‐Chemo Therapy of Breast Cancer

Advanced Science, EarlyView.
A CDSP NPs theranostic platform assembled from CDs and paclitaxel prodrugs is developed. CDSP NPs have long‐lasting NIR afterglow, penetrate deep tissues, and offer a high signal‐to‐noise ratio, enabling NIR afterglow imaging‐guided precise breast cancer removal to prevent recurrence.
Zixuan Li, Ranran Zhao, Qing Pei, Zhigang Xie, Min Zheng   +4 more
wiley   +1 more source

A comparison of the effects of oral vs. intravenous hydration on subclinical acute kidney injury: a protocol of a randomised controlled trial [PDF]

, 2017
Background: Optimal treatment for established renal failure is living donor kidney transplantation. However this pathway exposes healthy individuals to significant reduction in nephron mass via major surgical procedure.
Aitken, Emma, Clancy, Marc, Ghita, Ryan, Mackinnon, Shona   +3 more
core   +1 more source

Perioperative chemotherapy compared with surgery alone for resectable gastroesophageal adenocarcinoma: an FNCLCC and FFCD multicenter phase III trial.

Journal of Clinical Oncology, 2011
PURPOSE After curative resection, the prognosis of gastroesophageal adenocarcinoma is poor. This phase III trial was designed to evaluate the benefit in overall survival (OS) of perioperative fluorouracil plus cisplatin in resectable gastroesophageal ...
M. Ychou, V. Boige, J. Pignon, T. Conroy, O. Bouché, G. Lebreton, M. Ducourtieux, L. Bedenne, J. Fabre, B. Saint‐Aubert, J. Genève, P. Lasser, P. Rougier   +12 more
semanticscholar   +1 more source

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

The OneTogether collaborative approach to reduce the risk of surgical site infection: identifying the challenges to assuring best practice [PDF]

, 2015
Background: Surgical site infections (SSI) account for 16% of healthcare associated infections, and are associated with considerable morbidity, mortality and increased costs of care.
Gallagher, Rose, Neachell, Jonathan, Stott, Dawn, Topley, Katherine, Wilson, Jennie   +4 more
core   +1 more source