Results 121 to 130 of about 697,428 (396)

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Survival after postoperative morbidity: a longitudinal observational cohort study [PDF]

, 2014
Prolonged morbidity after surgery is associated with a risk of premature death for a longer duration than perhaps is commonly thought; however, this risk falls with time.
Emberton, M., Grocott, M.P.W., Haddad, F.S., Harris, S., Moonesinghe, S.R., Mythen, M.G., Rowan, K.M.   +6 more
core   +2 more sources

Immunocompatible Elastomer With Enhanced Fibrous Capsule‐Resistance and Elasticity by Water‐Induced Surface Phase Reconfiguration.

Advanced Science, EarlyView.
This study introduces a strategy for engineering heterogeneous surface and bulk structures within a single material, termed phase‐separation and underwater reconfiguration‐enhanced (PURE) elastomers. These elastomers combine high bulk elasticity with enhanced immunocompatibility at the surface.
Xianchi Zhou, Wenzhong Cao, Weifeng Liu, Wenbin Dai, Zihao Zhu, Fan Jia, Haijie Han, Ke Yao, Youxiang Wang, Jian Ji, Peng Zhang   +10 more
wiley   +1 more source

An EAACI position paper on the investigation of perioperative immediate hypersensitivity reactions

Allergy. European Journal of Allergy and Clinical Immunology, 2019
Perioperative immediate hypersensitivity reactions are rare. Subsequent allergy investigation is complicated by multiple simultaneous drug exposures, the use of drugs with potent effects and the many differential diagnoses to hypersensitivity in the ...
L. H. Garvey, D. Ebo, P. Mertes, P. Dewachter, T. Garcez, P. Kopač, J. Laguna, A. Chiriac, I. Terreehorst, S. Voltolini, K. Scherer   +10 more
semanticscholar   +1 more source

Salvage esophagectomy for unresectable locally advanced esophageal squamous cell carcinoma: Significant or not?

Annals of Gastroenterological Surgery, EarlyView.
Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki, Makoto Sakai, Takayoshi Watanabe, Makoto Sohda, Ken Shirabe   +4 more
wiley   +1 more source

Tourniquetless Total Knee Arthroplasty With Modern Perioperative Protocols Decreases Pain and Opioid Consumption in Women [PDF]

, 2018
Background This study examined whether a modern total knee arthroplasty (TKA) protocol without a tourniquet results in less patient-reported pain and in-hospital opioid consumption compared to TKA with a tourniquet.
Dilley, Julian E., Hood, Mark, Jr., Kheir, Michael M., Meneghini, R. Michael, Ziemba-Davis, Mary   +4 more
core   +1 more source

Effects of oral care on perioperative pediatric cancer patients

Dental, Oral and Maxillofacial Research, 2019
Objective: Problems faced by pediatric and adult cancer patients differ, as the former include late-stage complications and development/educational issues derived from a longer course of disease after treatment. Oral care, aiming to enhance patients’ QOL,
Toshiro Yamamoto, S. Takizawa, Makiko Otsubo, Yuki Miyagaki, Daisuke Matsui, Tomoko Iehara, N. Kanamura   +6 more
semanticscholar   +1 more source

Comparison between olanexidine gluconate and conventional antiseptics for surgical site infection in gastroenterological surgery: A meta‐analysis

Annals of Gastroenterological Surgery, EarlyView.
This meta‐analysis compared olanexidine gluconate (OLG) with conventional antiseptics on surgical site infections (SSIs) in gastroenterological surgery. OLG significantly reduced overall SSIs without statistical heterogeneity. Abstract Aim To compare the preventative effect of the new antiseptic olanexidine gluconate (OLG) with conventional antiseptics
Akihisa Matsuda, Takeshi Yamada, Kay Uehara, Aya Yamagishi, Hiroshi Yoshida   +4 more
wiley   +1 more source

Current status, trends, and controversies in the selection of gastrectomy procedures: Insights from two nationwide questionnaire surveys conducted over a 7‐year interval in Japan

Annals of Gastroenterological Surgery, EarlyView.
This study investigates the evolving trends and challenges in gastrectomy procedures in Japan, drawing on two nationwide surveys conducted in 2014 and 2021. Results show a significant shift toward minimally invasive and function‐preserving surgeries, such as laparoscopic and robot‐assisted gastrectomy, with an emphasis on enhancing postoperative ...
Koji Nakada, Hideyuki Kashiwagi, Shinichi Kinami, Hiroharu Yamashita, Nobuyoshi Hanyu, Atsushi Oshio, Michio Kaminishi, Yasuyuki Seto   +7 more
wiley   +1 more source

Reoperative pouch surgery for suspected Crohn's‐related complications aided by biologic coverage: Early experience from an inflammatory bowel disease center

Annals of Gastroenterological Surgery, EarlyView.
This paper demonstrates that revisional/redo ileal pouch anal anastomosis (IPAA) surgery with concurrent biologic therapy provides a viable, stoma‐free alternative for patients with Crohn's disease‐like complications, showing a high functioning pouch rate and expanding options for managing pouch failure.
Mehmet Gulmez, Daniel J. Wong, Ariela K. Holmer, Eren Esen, Shannon Chang, Arman Erkan, David Hudesman, Andre da Luz Moreira, Feza H. Remzi   +8 more
wiley   +1 more source