Results 61 to 70 of about 511,668 (346)

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

Advanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma, Chengke Xie, Chengyu Liao, Binting Huang, Siqi Liu, Junhua Kong, Xiaotong Fan, Zibiao Li, Shi Chen, Chaobin He   +9 more
wiley   +1 more source

Perioperative Risk: Short Review of Current Approach in Non Cardiac Surgery

Journal of Cardiovascular Development and Disease
The rate of major surgery is constantly increasing worldwide, and approximately 85% are non-cardiac surgery. More than half of patients over 45 years presenting for non-cardiac surgical interventions have cardiovascular risk factors, and the most common:
Andreea Boghean, Cristian Guțu, Dorel Firescu   +2 more
doaj   +1 more source

Undertaking the surgical count: An observational study

Journal of Perioperative Nursing, 2021
Objective: To systematically measure and describe perioperative nurses’ surgical count practices using the Surgical Count Observational Tool, to measure conformity with standardised processes and identify barriers and enablers influencing nurses ...
Victoria Warwick, Brigid Gillespie, Anne McMurray, Karen Clark-Burg   +3 more
doaj   +1 more source

Avoidable blood transfusions [PDF]

, 2019
Si discute l'importanza di una analisi accurata nel definire il fattore di rischio di trasfusioni nella genesi della trombosi profonda delle vene degli arti ...
Sterpetti, Antonio V.
core   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

Advanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba, Giulia Puliatti, Domenica Donatella Li Puma, Bruno Bandiera, Beatrice Cannata, Maria Elena Marcocci, Nicolina Castagno, Irene Contento, Salvatore Impemba, Mariarosa Scognamiglio, Rocco Di Girolamo, Vincenzo Naddeo, Patrizia Canton, Carmine Capacchione, Laura Sposito, Martina Albini, Francesco Pastore, Silvia Baroni, Alfonso Grassi, Claudio Grassi, Roberto Piacentini   +20 more
wiley   +1 more source

Peripheral memory B cell population maintenance and long-term survival after perioperative chemoimmunotherapy in NSCLC (NADIM trial)

OncoImmunology
Perioperative chemoimmunotherapy has significantly improved survival rates for non-small cell lung cancer (NSCLC). However, current tissue biomarkers remain inadequate, underscoring the need for more sensitive and accessible alternatives to monitor ...
Belén Sierra Rodero, Cristina Martínez-Toledo, Ernest Nadal, Marta Molina-Alejandre, Rosario García Campelo, Ángeles Gil-González, Bartomeu Massuti, Aránzazu García-Grande, Manuel Dómine, Amelia Insa, Javier de Castro Carpeño, Gerardo Huidobro Vence, Margarita Majem, Alex Martinez-Marti, Diego Megias, Daniel Lobato, Ana Collazo-Lorduy, Virginia Calvo, Mariano Provencio, Alberto Cruz-Bermúdez   +19 more
doaj   +1 more source

Managing the Complex Patient with Degenerative Cervical Myelopathy: How to Handle the Aging Spine, the Obese Patient, and Individuals with Medical Comorbidities. [PDF]

, 2018
Degenerative cervical myelopathy (DCM) is the most common cause of nontraumatic spinal cord injury worldwide. Even relatively mild impairment in functional scores can significantly impact daily activities.
Gillick, John, Harrop, James, Rymarczuk, George, Stricsek, Geoffrey   +3 more
core   +1 more source

Tourniquetless Total Knee Arthroplasty With Modern Perioperative Protocols Decreases Pain and Opioid Consumption in Women [PDF]

, 2018
Background This study examined whether a modern total knee arthroplasty (TKA) protocol without a tourniquet results in less patient-reported pain and in-hospital opioid consumption compared to TKA with a tourniquet.
Dilley, Julian E., Hood, Mark, Jr., Kheir, Michael M., Meneghini, R. Michael, Ziemba-Davis, Mary   +4 more
core   +1 more source

Disruption of Sulfur Metabolism and Redox Homeostasis in Staphylococcus aureus Using Mechanically Robust Antibiofilm Ti‐Bi Alloys

Advanced Materials Interfaces, EarlyView.
Titanium (Ti) and bismuth (Bi) are selected as alloying elements for the preparation of the Ti‐Bi binary alloy system. Biofilm formation is found to be inhibited by bismuth through the disruption of sulfur metabolism and redox homeostasis, as well as through the direct downregulation of biofilm‐associated proteins.
Lei Shi, Chen Chen, Fupeng Li, Kexin Liu, Kewei Rong, Tong Xing, Tingxian Guo, Kai Huang, Shengbing Yang, Wentao Lin, Jie Zhao   +10 more
wiley   +1 more source

Antimicrobial Multi‐Assay Evaluation of (Al‐Doped ZnO)‐Ag and TiO2‐Ag Nanocoatings: Impact of Direct and Indirect Mechanisms

Advanced Materials Interfaces, EarlyView.
This work explores the antimicrobial action of AZO‐Ag and TiO2‐Ag nanocoatings on plastic, demonstrating good efficacy against highly‐critical antibiotic‐resistant bacteria, yeast, and virus. A multi‐assay approach is here exploited to inspect the contribution of direct and indirect antimicrobial mechanisms, and potential human toxicity is also ...
Damiano Squitieri, Roberta Vitali, Cecilia Bartoleschi, Giulia Lombardini, Margherita Cacaci, Lorenzo Degli Esposti, Camilla Fusacchia, Skerxho Osmani, Luca Gavioli, Francesca Bugli, Daniele Valerini   +10 more
wiley   +1 more source