Results 91 to 100 of about 184,347 (251)

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

open access: yesHepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince   +30 more
wiley   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

open access: yesBMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang   +8 more
wiley   +1 more source

Factors associated with cardiovascular events after simultaneous liver–kidney transplant from the US Multicenter Simultaneous Liver–Kidney Transplant Consortium

open access: yesHepatology Communications, EarlyView., 2022
Abstract Cardiovascular disease is a leading complication after both liver and kidney transplantation. Factors associated with and rates of cardiovascular events (CVEs) after simultaneous liver–kidney transplant (SLKT) are unknown. This was a retrospective cohort study of adult SLKT recipients between 2002 and 2017 at six centers in six United Network ...
Jennifer Jo   +19 more
wiley   +1 more source

Surgical management of persistent gingival recession after sepsis‐associated gingival necrosis in a patient with systemic lupus erythematosus: A case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Sepsis‐associated gingival necrosis is an uncommon oral manifestation that may result in extensive gingival recession after the resolution of the acute phase. Methods This report presents the 2‐year follow‐up of periodontal management in a 38‐year‐old woman with systemic lupus erythematosus, who developed septic shock accompanied by
Risako Mikami   +4 more
wiley   +1 more source

From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real‐world platform for integrating prevention, diagnosis, treatment, and survivorship across the cancer continuum.
Leonardo Oliveira Reis
wiley   +1 more source

Ultrasound-based assessment of muscle mass is associated with early recovery after kidney transplant: a prospective single-center study

open access: yesBMC Anesthesiology
Background Low muscle mass and frailty are associated with worse perioperative outcomes. However, traditional modalities for quantifying muscle mass are limited, costly, may require radiation exposure, and can be unreliable with kidney failure.
Nicholas V. Mendez   +5 more
doaj   +1 more source

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Performance of routine surveillance diagnostics of external ventricular drain-associated infections in a critical care setting: a retrospective cohort study

open access: yesBMC Infectious Diseases
Introduction External ventricular drains (EVDs) are crucial for treating neurocritically ill patients but are complicated by feared EVD-associated infections (EVDIs) in up to 35% of all inserted drains, contributing significantly to morbidity, mortality ...
Marcus Ståhlberg   +6 more
doaj   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai   +12 more
wiley   +1 more source

The Effect of Clinical Ambiguity on the Decision-Making Process Among Intensive Care Unit Providers in Northern America Using Clinical Vignettes in Mixed Methods Study

open access: yesJournal of Multidisciplinary Healthcare
Desiree Fleck,1,* Hossam Gad,2,* Beth Hogan Quigley,1,* Mohamed Antar,2 Ahmed Sayed Ahmed,3 Mohamed A Mahmoud,3 Krzysztof Laudanski2 1Department of Nursing, University of Pennsylvania, Philadelphia, PA, USA; 2Department of ...
Fleck D   +6 more
doaj  

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