Results 121 to 130 of about 145,312 (293)

Timing and Perioperative Care in Intracranial Aneurysm Surgery

open access: hybrid, 1974
William E. Hunt, Edward J. Kosnik
openalex   +1 more source

Long‐Term Follow‐Up After Direct‐Flow Transcatheter Aortic Valve Implantation: A Single Center Experience

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Aims Valve degeneration after DirectFlow implantation poses a challenge for valve‐in‐valve procedures due to its fragile polymeric structure and embolization risk. This study analyzes long‐term follow‐up of patients who underwent TAVI with DF to understand valve degeneration tendencies.
Dan M. Prunea   +11 more
wiley   +1 more source

Bioprosthetic Valve Fracturing in Valve‐in‐Valve TAVI: Clinical and Echocardiographic Outcomes in Failing Perimount Aortic Bioprostheses—A Multicenter Registry

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Data comparing clinical and hemodynamic outcomes of bioprosthetic valve fracturing (BVF) and “standard”‐postdilatation during valve‐in‐valve transcatheter heart valve implantation (ViV‐TAVI) are lacking. The authors aimed to analyze hemodynamic and clinical outcomes of BVF compared to “standard”‐postdilatation during ViV‐TAVI ...
Hendrik Ruge   +14 more
wiley   +1 more source

Severe Vasoplegic Syndrome Treated with Angiotensin II and Hemoadsorption Therapy after Cardiac Surgery

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Vasoplegic syndrome (VS) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). The main pathophysiology mechanism of VS includes a systemic inflammatory response syndrome due to surgical trauma, release of pro‐inflammatory mediators caused by blood contact with foreign surfaces of heart‐lung machine (pump and tubing)
Matteo Lucchelli   +3 more
wiley   +1 more source

Targeted Delivery of Lidocaine in Breast Cancer Cells via Zeolitic Imidazolate Framework‐8 Nanoparticles

open access: yesChemPhysChem, EarlyView.
Drug repositioning of lidocaine from local anesthetic to theranostic agent for breast cancer cells is enhanced by its encapsulation inside ZIF‐8 metal–organic framework. The aim of this article is to use zeolitic imidazolate framework‐8 (ZIF‐8) metal–organic frameworks (MOFs) as drug delivery system for lidocaine, a local anesthetic with recently ...
Nicola di Nicola   +7 more
wiley   +1 more source

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima   +11 more
wiley   +1 more source

Relationship between Dose, Factor IX Activity Levels and Bleeding Probability for rIX‐FP Prophylaxis in Hemophilia B: A Repeated Time‐to‐Event Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
In hemophilia B, pharmacokinetic (PK)‐guided dosing of extended half‐life factor IX (EHL‐FIX) concentrates can secure targeted FIX exposure. Target FIX activity levels in plasma should be individually set primarily taking bleeding tendency into account, alongside the presence of target joints, physical activity, and preferred dosing schedules. In other
Sjoerd F. Koopman   +4 more
wiley   +1 more source

A contemporary simple risk score for prediction of severe acute kidney injury after heart transplantation

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1166-1175, April 2025.
A contemporary simple risk score for prediction of severe AKI after HT. Abstract Background The aim of this study was to develop a simple risk score to estimate severe acute kidney injury (AKI) risk based on a large contemporary heart transplantation (HT) cohort.
Shuangshuang Zhu   +10 more
wiley   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo   +7 more
wiley   +1 more source

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