Results 161 to 170 of about 4,932,113 (241)

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai   +12 more
wiley   +1 more source

Treatment with angiotensin II in COVID-19 patients may not be beneficial

open access: yesCritical Care, 2020
Susanne Rysz   +5 more
doaj   +1 more source

Exposure–Response Analysis of Enfortumab Vedotin Plus Pembrolizumab as First‐Line Therapy for Locally Advanced or Metastatic Urothelial Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Enfortumab vedotin is a nectin‐4‐directed antibody–drug conjugate currently approved in combination with pembrolizumab for the first‐line treatment of locally advanced or metastatic urothelial cancer. Here we describe the exposure–response relationship between enfortumab vedotin exposures and efficacy/safety endpoints in patients who received ≥1 dose ...
Vaishali L. Chudasama   +9 more
wiley   +1 more source

Perioperative Care of Kidney Transplant Recipients: A Cross-Sectional Canadian Multidisciplinary Survey. [PDF]

open access: yesCan J Kidney Health Dis
McGinn RN   +9 more
europepmc   +1 more source

A Practical Guide to Implementing Real‐World Evidence as Primary Basis for Approval and Label Expansion

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
In June 2026, the FDA issued a revised draft guidance describing the circumstances in which one adequate and well‐controlled clinical investigation plus confirmatory evidence may satisfy the statutory substantial evidence standard for establishing efficacy and safety. Confirmatory evidence includes real‐world evidence (RWE).
Tracy J. Mayne   +2 more
wiley   +1 more source

Development of consensus-based standards for a National Clinical Audit of Perioperative Care: protocol for a modified Delphi consensus study. [PDF]

open access: yesBMJ Open
West MA   +10 more
europepmc   +1 more source

Navigating the Role of Clinical Pharmacists in Integrative Oncology Care Teams: Time to Create Higher Training and Practice Standards

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Integrative oncology (IO) programs are committed to offer evidence‐based complementary medicine within conventional cancer care, addressing quality of life‐related concerns. As part of a multidisciplinary team, clinical pharmacists provide guidance on potential effectiveness and safety of herbal supplement use, identifying potential toxicities and herb–
Eran Ben‐Arye   +3 more
wiley   +1 more source

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