Results 201 to 210 of about 158,366 (318)

Radical Cystectomy in the Elderly: National Trends and Disparities in Perioperative Outcomes and Quality of Care [PDF]

open access: bronze, 2013
Florian Roghmann   +13 more
openalex   +1 more source

GDF15 Analogues Acting as GFRAL Ligands

open access: yesChemMedChem, EarlyView.
Considering the great importance of the GDF15/GRAL/RET signalling pathway, this review focuses on GDF15‐derived analogues able to act either as GFRAL agonists or antagonists, investigating their possible pharmacological applications in the treatment of GDF15‐related conditions, such as obesity and diabetes (agonist), or cancer‐induced nausea and ...
Andrea Di Santo   +8 more
wiley   +1 more source

The Role of the Anesthesiologist in Fast-Track Surgery: From Multimodal Analgesia to Perioperative Medical Care

open access: bronze, 2007
Paul F. White   +5 more
openalex   +1 more source

Key interventions and outcomes in perioperative care pathways in emergency laparotomy: a systematic review. [PDF]

open access: yesWorld J Emerg Surg
Harji DP   +5 more
europepmc   +1 more source

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima   +11 more
wiley   +1 more source

Identification and Clinical Evaluation of Potential Biomarkers for Breast Cancer Resistance Protein (BCRP/ABCG2)

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clinical inhibition and genetic variation of the Breast Cancer Resistance Protein (BCRP/ABCG2) efflux transporter can significantly influence drug exposure, highlighting the need for reliable BCRP functional biomarkers. This study aimed to identify and evaluate biomarkers predictive of BCRP function in humans.
Andrew M. Riselli   +16 more
wiley   +1 more source

Is the panic about beta-blockers in perioperative care justified? [PDF]

open access: bronze, 2014
Thomas F. Lüscher   +3 more
openalex   +1 more source

The Drug Titration Paradox Updated and Reinterpreted: With Perfect Titration, Dose and Effect Will Be Uncorrelated

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The drug titration paradox is a clinical observation at a population level whereby patients receiving a high dose of medication appear to have a lower‐than‐average clinical effect, and patients receiving a low dose of medication appear to have a higher‐than‐average clinical effect.
Elie Sarraf, Klaske van Heusden
wiley   +1 more source

Home - About - Disclaimer - Privacy