Results 41 to 50 of about 134,072 (327)

The State of Research Funding for Interventional Chronic Pain Therapies

Journal of Pain Research, 2023
Sunil Agarwal,1 Christopher Gharibo,2 Michael E Schatman2,3 1Department of Anesthesiology, Division of Pain Medicine, Emory University School of Medicine, Atlanta, GA, USA; 2Department of Anesthesiology, Perioperative Care & Pain Medicine, NYU Grossman ...
Agarwal S, Gharibo C, Schatman ME
doaj  

ECMO for Metabolic Crisis in a Patient with Mitochondrial Disease

Case Reports in Anesthesiology, 2021
Patients with mitochondrial disease exhibit disrupted pyruvate oxidation, resulting in intraoperative and perioperative physiologic derangements. Increased enzymatic conversion of pyruvate via lactate dehydrogenase during periods of fasting or stress can
Sonal Sharma, Clifford Deerman, Michael H. Andreae, Conrad Myler   +3 more
doaj   +1 more source

The Foundational Capabilities of Large Language Models in Predicting Postoperative Risks Using Clinical Notes [PDF]

Published at npj Digital Medicine (2025)
Clinical notes recorded during a patient's perioperative journey holds immense informational value. Advances in large language models (LLMs) offer opportunities for bridging this gap. Using 84,875 pre-operative notes and its associated surgical cases from 2018 to 2021, we examine the performance of LLMs in predicting six postoperative risks using ...
arxiv   +1 more source

Update in Perioperative Medicine 2011 [PDF]

Journal of General Internal Medicine, 2011
The field of perioperative medicine continues to mature as evidenced by the growing number of high-quality articles published each year. This is encouraging given the increasingly complex patient population that routinely undergoes major surgery. Furthermore, as surgeons have become more sub-specialized, there is increased reliance on the generalist to
Amir K. Jaffer, Paul J. Grant, Steven L. Cohn, Gerald W. Smetana   +3 more
openaire   +2 more sources

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

Advanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang, Li Zhang, Sen Chen, Le Xie, Yue Qiu, Chenyang Kong, Ge Yin, Weijia Kong, Yu Sun   +8 more
wiley   +1 more source

VoPo leverages cellular heterogeneity for predictive modeling of single-cell data

Nature Communications, 2020
Single-cell technologies are increasingly prominent in clinical applications, but predictive modelling with such data in large cohorts has remained computationally challenging.
Natalie Stanley, Ina A. Stelzer, Amy S. Tsai, Ramin Fallahzadeh, Edward Ganio, Martin Becker, Thanaphong Phongpreecha, Huda Nassar, Sajjad Ghaemi, Ivana Maric, Anthony Culos, Alan L. Chang, Maria Xenochristou, Xiaoyuan Han, Camilo Espinosa, Kristen Rumer, Laura Peterson, Franck Verdonk, Dyani Gaudilliere, Eileen Tsai, Dorien Feyaerts, Jakob Einhaus, Kazuo Ando, Ronald J. Wong, Gerlinde Obermoser, Gary M. Shaw, David K. Stevenson, Martin S. Angst, Brice Gaudilliere, Nima Aghaeepour   +29 more
doaj   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Perioperative Medicine [PDF]

Anesthesiology, 2010
J Lance Lichtor, Joseph F. Antognini
  +9 more sources

Lidocaine for postoperative pain after cardiac surgery: a systematic review

Journal of Cardiothoracic Surgery, 2021
Objective Lidocaine is one of the most widely used local anesthetics with well-known pharmacological properties. The purpose of this systematic review is to investigate the effects of lidocaine on postoperative pain scores and recovery after cardiac ...
Michael R. Boswell, Rajat N. Moman, Melissa Burtoft, Harrison Gerdes, Jacob Martinez, Danielle J. Gerberi, Erica Wittwer, M. Hassan Murad, W. Michael Hooten   +8 more
doaj   +1 more source

Machine Learning‐Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi‐Omics

Advanced Science, EarlyView.
This study develops noninvasive clinical‐radiomic models using preoperative CT images to predict the malignant potential of pancreatic cystic lesions. It demonstrates the models' high accuracy across various datasets, with AUCs exceeding 0.92. Additionally, multi‐omics analyses uncover key biological mechanisms, including secretion function and lipid ...
Sihang Cheng, Ge Hu, Shenbo Zhang, Rui Lv, Limeng Sun, Zhe Zhang, Zhengyu Jin, Yanyan Wu, Chen Huang, Lu Ye, Zhe‐Sheng Chen, Yunlu Feng, Aiming Yang, Zhiwei Wang, Huadan Xue   +14 more
wiley   +1 more source