Results 161 to 170 of about 250,732 (360)

Provisional Dynamic Hinged External Fixation Enables Arthroscopy‐Assisted Circular Frame Reconstruction of Complex Tibial Plateau Fractures

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To describe the surgical technique and early operative outcomes of using a provisional dynamic external fixator to facilitate arthroscopic‐assisted reduction of complex tibial plateau fractures. Methods Between 2014 and 2024, we conducted a retrospective single‐center case series of Schatzker IV‐VI tibial plateau fractures treated with ...
Ilan Y. Mitchnik   +7 more
wiley   +1 more source

Using machine learning techniques to develop forecasting algorithms for postoperative complications: Protocol for a retrospective study [PDF]

open access: yes, 2018
Avidan, Michael Simon   +11 more
core   +2 more sources

Current evidence and insights on single vs. double dose of basiliximab in adult solid organ transplant recipients: A systematic review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani   +4 more
wiley   +1 more source

Mechanism‐informed machine learning for individualized tacrolimus dose adjustment in the early post‐kidney transplant period

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus dosing in the early post‐kidney transplant period is challenging due to a narrow therapeutic index and substantial interindividual pharmacokinetic (PK) variability. This study aimed to develop and validate mechanism‐informed machine learning (ML) models to support individualized tacrolimus dosing during this critical period ...
Hui Yu   +4 more
wiley   +1 more source

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis   +5 more
wiley   +1 more source

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