Results 101 to 110 of about 425,151 (292)

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Peripheral arterial disease and type 2 diabetes: Older patients still exhibit a survival benefit from glucose control

Diabetes & Vascular Disease Research, 2020
Objective: To investigate a possible beneficial effect of strict glycaemic control on all-cause mortality in patients with peripheral arterial disease and type 2 diabetes mellitus. Methods: A total of 367 mainly older peripheral arterial disease patients
Clemens Höbaus, Carsten Thilo Herz, Thomas Wrba, Renate Koppensteiner, Gerit-Holger Schernthaner   +4 more
doaj   +1 more source

Increased systemic inflammation is associated with cardiac and vascular dysfunction over the first 12 weeks of antiretroviral therapy among undernourished, HIV-infected adults in Southern Africa. [PDF]

, 2015
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.INTRODUCTION ...
Bala, J, Bestawros, M, Blevins, M, Canipe, A, Chidumayo, T, Filteau, S, Heimburger, DC, Kelly, P, Koethe, JR, Shepherd, BE   +9 more
core   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

The Peripheral Arterial disease study (PERART/ARTPER): prevalence and risk factors in the general population

BMC Public Health, 2010
Background The early diagnosis of atherosclerotic disease is essential for developing preventive strategies in populations at high risk and acting when the disease is still asymptomatic.
Vicheto Marisa, Sorribes Marta, Toran Pere, Pera Guillem, Baena-Díez José, Forés Rosa, Alzamora María, Reina María, Sancho Amparo, Albaladejo Carlos, Llussà Judith   +10 more
doaj   +1 more source

Genetic variation in rs7903146 correlating with peripheral arterial disease in long-standing type 2 diabetes

Diabetes & Vascular Disease Research, 2020
Aim: The aim of this study was to investigate the association between the transcription factor 7-like 2 gene ( TCF7L2 ) rs7903146 polymorphism and peripheral arterial disease in type 2 diabetes.
Eu Jeong Ku, Gun Woo Won, Yong Hee Lee, Dong-Hwa Lee, Hyun Jeong Jeon, Tae Keun Oh   +5 more
doaj   +1 more source

Associations of Weight Change With Changes in Calf Muscle Characteristics and Functional Decline in Peripheral Artery Disease. [PDF]

, 2019
Background Among people with lower extremity peripheral artery disease, obesity is associated with faster functional decline than normal weight. The association of weight loss with functional decline in peripheral artery disease is unknown.
Bazzano, Lydia A, Criqui, Michael H, Ferrucci, Luigi, Guralnik, Jack M, Kibbe, Melina R, Leeuwenburgh, Christiaan, McDermott, Mary M, Polonsky, Tamar S, Sufit, Robert L, Tian, Lu, Zhang, Dongxue   +10 more
core  

Assessment of the peripheral microcirculation using computer-assisted venous congestion plethysmography in post-traumatic complex regional pain syndrome type I [PDF]

, 2001
In complex regional pain syndrome type I (CRPS-I), edema of the affected limb is a common finding. Therefore, the changes in macro- and microcirculatory parameters were investigated to elucidate the underlying pathophysiology.
Christ, Frank, Gradl, Georg, Schürmann, Matthias, Wipfel, Alexander, Zaspel, Johannes   +4 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Peripheral Arterial Disease Study (PERART): Prevalence and predictive values of asymptomatic peripheral arterial occlusive disease related to cardiovascular morbidity and mortality

BMC Public Health, 2007
Background The early diagnosis of atherosclerotic disease is essential for developing preventive strategies in populations at high risk and acting when the disease is still asymptomatic. A low ankle-arm index (AAI) is a good marker of vascular events and
Bundó Magda, Llussà Judith, Albaladejo Carlos, Reina María, Pera Guillem, Vicheto Marisa, Toran Pere, Forés Rosa, Sorribes Marta, Baena-Díez José, Alzamora María, Sancho Amparo, Heras Antonio, Rubiés Joan, Arenillas Juan   +14 more
doaj   +1 more source