Results 161 to 170 of about 904,031 (397)

FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine

open access: yesAdvanced Science, EarlyView.
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang   +15 more
wiley   +1 more source

Next‐Generation Piezoelectric Materials in Wearable and Implantable Devices for Continuous Physiological Monitoring

open access: yesAdvanced Science, EarlyView.
An analysis of literature trends and a historical overview of organic and inorganic piezoelectric materials, focusing on their structural diversity, functional mechanisms, and inherent characteristics. It then explores cutting‐edge developments in material synthesis, fabrication processes, and performance optimization, highlighting their applicability ...
Bangul Khan   +7 more
wiley   +1 more source

Mortality over a period of 10 years in patients with peripheral arterial disease.

open access: yesNew England Journal of Medicine, 1992
M. Criqui   +6 more
semanticscholar   +1 more source

The anti-atherogenic effects of thiazolidinediones [PDF]

open access: yes, 2007
The thiazolidinediones (TZDs) rosiglitazone (ROS) and pioglitazone (PIO) are insulin-sensitising agents widely used to treat patients with type 2 diabetes mellitus (T2DM). Thiazolidinediones significantly improve glycaemic control in diabetics by reduced
Honisett, Suzy   +2 more
core  

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

open access: yesAdvanced Science, EarlyView.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi   +18 more
wiley   +1 more source

Peripheral arterial disease as a predictor of outcome after renal transplantation [PDF]

open access: bronze, 1998
Heikki Mäkisalo   +6 more
openalex   +1 more source

Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2‐Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction

open access: yesAdvanced Science, EarlyView.
SCAP/ARDS patients show reduced unsaturated fatty acids (UFAs) but higher PARK7 and lactate in plasma. PARK7 correlates positively with lactate and negatively with UFAs. Pulmonary endothelial cell multi‐omics show FADS1/2 downregulation and impaired PUFA metabolism. Lactate boosts PARK7 via H3K14 lactylation, and PARK7 then restores FADS1/2.
Jian Xu   +11 more
wiley   +1 more source

Optimal management of infrainguinal arterial occlusive disease

open access: yesVascular Health and Risk Management, 2014
David J Pennywell, Tze-Woei Tan, Wayne W Zhang Division of Vascular and Endovascular Surgery, Louisiana State University Health Shreveport, Shreveport, LA, USA Abstract: Peripheral arterial occlusive disease is becoming a major health problem in Western
Pennywell DJ, Tan TW, Zhang WW
doaj  

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