Results 71 to 80 of about 255,745 (263)

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

Advanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan, Peng Li, Yue Wang, Xin Qi, Wanyu Wang, Yongzhong Cheng, Huabin Zhang, Xin Hu, Xiang Gao   +8 more
wiley   +1 more source

P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE

Artery Research, 2015
Increased arterial stiffness occurs in older patients with peripheral arterial disease (PAD). In this study we compared arterial stiffness and central hemodynamic parameters in young (< 60 years of age) PAD patients and controls.
Mariella Catalano*, Giovanni Scandale, Gabriel Dimitrov, Marzio Minola, Martino Recchia, Francesca Galli, Gianni Carzaniga, Maria Carotta   +7 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Peripheral arterial disease and type 2 diabetes: Older patients still exhibit a survival benefit from glucose control

Diabetes & Vascular Disease Research, 2020
Objective: To investigate a possible beneficial effect of strict glycaemic control on all-cause mortality in patients with peripheral arterial disease and type 2 diabetes mellitus. Methods: A total of 367 mainly older peripheral arterial disease patients
Clemens Höbaus, Carsten Thilo Herz, Thomas Wrba, Renate Koppensteiner, Gerit-Holger Schernthaner   +4 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

The Peripheral Arterial disease study (PERART/ARTPER): prevalence and risk factors in the general population

BMC Public Health, 2010
Background The early diagnosis of atherosclerotic disease is essential for developing preventive strategies in populations at high risk and acting when the disease is still asymptomatic.
Vicheto Marisa, Sorribes Marta, Toran Pere, Pera Guillem, Baena-Díez José, Forés Rosa, Alzamora María, Reina María, Sancho Amparo, Albaladejo Carlos, Llussà Judith   +10 more
doaj   +1 more source

Genetic variation in rs7903146 correlating with peripheral arterial disease in long-standing type 2 diabetes

Diabetes & Vascular Disease Research, 2020
Aim: The aim of this study was to investigate the association between the transcription factor 7-like 2 gene ( TCF7L2 ) rs7903146 polymorphism and peripheral arterial disease in type 2 diabetes.
Eu Jeong Ku, Gun Woo Won, Yong Hee Lee, Dong-Hwa Lee, Hyun Jeong Jeon, Tae Keun Oh   +5 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Peripheral Arterial Disease Study (PERART): Prevalence and predictive values of asymptomatic peripheral arterial occlusive disease related to cardiovascular morbidity and mortality

BMC Public Health, 2007
Background The early diagnosis of atherosclerotic disease is essential for developing preventive strategies in populations at high risk and acting when the disease is still asymptomatic. A low ankle-arm index (AAI) is a good marker of vascular events and
Bundó Magda, Llussà Judith, Albaladejo Carlos, Reina María, Pera Guillem, Vicheto Marisa, Toran Pere, Forés Rosa, Sorribes Marta, Baena-Díez José, Alzamora María, Sancho Amparo, Heras Antonio, Rubiés Joan, Arenillas Juan   +14 more
doaj   +1 more source