Results 91 to 100 of about 88,519 (382)

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

Optimal management of infrainguinal arterial occlusive disease

Vascular Health and Risk Management, 2014
David J Pennywell, Tze-Woei Tan, Wayne W Zhang Division of Vascular and Endovascular Surgery, Louisiana State University Health Shreveport, Shreveport, LA, USA Abstract: Peripheral arterial occlusive disease is becoming a major health problem in Western
Pennywell DJ, Tan TW, Zhang WW
doaj  

APOC1 rs445925 and rs4420638 polymorphic variants as genetic predictors of occlusive peripheral arterial disease of lower extremities

Российский кардиологический журнал
Aim. To study the involvement of APOC1 rs445925 and rs4420638 single nucleotide polymorphisms (SNP) in the development of occlusive peripheral arterial disease (PAD) of lower extremities.Material and methods. The study included 1278 people, including 630
S. N. Zhabin, V. A. Lazarenko, Yu. E. Azarova, E. Yu. Klesova, M. A. Bykanova, S. S. Chernousova, D. A. Bashkatov, M. I. Churnosov, M. A. Solodilova, A. V. Polonikov   +9 more
doaj   +1 more source

Endovascular Revascularization for Aortoiliac Occlusive Disease

대한영상의학회지, 2021
Peripheral arterial disease is an occlusive condition commonly involving the lower extremity vessels. When the aortoiliac region is affected by this disease, conventional management involves surgical bypass and endovascular treatment has been mainly ...
Myungsu Lee
doaj   +1 more source

Ankle brachial index combined with Framingham risk score to predict cardiovascular events and mortality - A meta-analysis [PDF]

, 2008
CONTEXT: Prediction models to identify healthy individuals at high risk of cardiovascular disease have limited accuracy. A low ankle brachial index (ABI) is an indicator of atherosclerosis and has the potential to improve prediction.
,, Bouter, L. M., Breteler, M. M. B., Butcher, I., Chambless, L. E., Criqui, M. H., Curb, J. D., Cushman, M., d'Agostino, R. B., deBacker, G., Dekker, J. M., Dramaix, M., Ferrucci, L., Folsom, A. R., Fowkes, F. G. R., Fronek, A., Guralnik, J., Hamman, R., Heald, C. L., Hedblad, B., Heine, R. J., Hiatt, W. R., Hirsch, A. T., Hofman, A., Hooi, J. D., Hunink, M. G. M., Jamrozik, K., Knottnerus, J. A., Kornitzer, M., Langer, R. D., Lee, A. J., Lee, R. J., Masaki, K. H., McDermott, M. M., McDermott, M. M., Murabito, J. M., Murray, G. D., Newman, A. B., Nijpels, G., Norman, P. E., Ogren, M., Price, J. F., Resnick, H. E., Rodriquez, B. L., Stehouwer, C. D. A., Stoffers, H. E., Sutton-Tyrrell, K., Wautrecht, J-C., Witteman, J. C.   +48 more
core   +5 more sources

Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery

Advanced Science, EarlyView.
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li, Yunfei Dong, Yaode He, Juanjuan Zheng, Hui Liu, Lu Li, Xiaoxu Hao, Yanli Zhao, Zefeng Yang, Yuankai Sun, Zhiwei Du, Bo Zhao, Weihang Zhou, Honghui Wu, Tianyuan Zhang, Jiahe Wu, Xiangrui Liu, Xianzhen Yin, Zhicai Chen, Rui Xue, Min Lou, Zhen Gu, Xinchi Jiang, Jianqing Gao   +23 more
wiley   +1 more source

Assessment of occlusive arterial disease of abdominal aorta and lower extremities arteries: value of multidetector CT angiography using an adaptive acquisition method [PDF]

, 2018
We evaluated 16-detector-row CT in the assessment of occlusive peripheral arterial disease (PAD) of the abdominal aorta and lower extremities using an adaptive method of acquisition to optimise arterial enhancement especially for the distal foot arteries.
Denys, A., Doenz, F., Guntern, D., Laswed, T., Qanadli, S., Rizzo, E., Schnyder, P.   +6 more
core  

Non-Contrast-Enhanced MR Angiography at 3 Tesla in Patients with Advanced Peripheral Arterial Occlusive Disease

PLoS ONE, 2014
Purpose The aim of this study was to assess the diagnostic performance of ECG-gated non-contrast-enhanced quiescent interval single-shot (QISS) magnetic resonance angiography at a magnetic field strength of 3 Tesla in patients with advanced peripheral ...
K. Thierfelder, G. Meimarakis, K. Nikolaou, W. Sommer, P. Schmitt, P. Kazmierczak, M. Reiser, D. Theisen   +7 more
semanticscholar   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Assessment and management of diabetic ulcers in the primary health care setting [PDF]

, 2008
John is a 62 year old gentleman who has been suffering from type 2 Diabetes Mellitus for the past 7 years. He presents to the clinic with an ulcer 5 mm in diameter on the lateral aspect of the right foot near the metatarsophalangeal joint area. The ulcer
De Gabriele, Renzo
core