Results 241 to 250 of about 21,037 (302)

Selective Deletion of NBCe1 in Reactive Astrocytes Attenuates Ischemic Stroke Brain Damage

Glia, Volume 73, Issue 12, Page 2386-2406, December 2025.
Main Points NBCe1 is upregulated in reactive astrocytes following ischemic stroke. Deletion of astrocytic Nboe1 reduces stroke volume, preserves AQP4 polarization, reduces BBB permeability, and improves neurological function after ischemic stroke. ABSTRACT The electrogenic sodium bicarbonate transporter 1 (NBCe1/Slc4a4), predominantly expressed in ...
Okan Capuk, Elise Berthold, Kathiravan Kaliyappan, Mansi Avunoori, Rajesh Muduganti, Sanjana Krishna, Shamseldin Metwally, Mary McFarland, Shanshan Song, Victoria Fiesler, Sydney Fischer, Lesley M. Foley, T. Kevin Hitchens, Susannah Waxman, Ian A. Sigal, Shefeeq M. Theparambil, Gulnaz Begum   +16 more
wiley   +1 more source

Malignant Anomalous Aortic Origin of the Left Main Coronary Artery Managed by Ostial Reimplantation: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Anomalous origin of the left main coronary artery (LMCA) from the right coronary sinus with an interarterial course is a rare congenital variant associated with a high risk of myocardial ischemia and sudden cardiac death. We describe a 39‐year‐old man presenting with exertional chest pressure and dyspnea whose coronary CT angiography revealed ...
Biruk T. Mengistie, Chernet T. Mengistie, Asteway M. Haile, Nahom D. Gerer, Samuel Mesfin Girma, Elezer B. Zewde   +5 more
wiley   +1 more source

Budd–Chiari Syndrome in the Background of Chronic Kidney Disease: A Hypercoagulability‐Driven Association or Coincidence? A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Budd–Chiari syndrome (BCS) is a rare condition characterized by hepatic venous outflow obstruction and is often associated with thrombosis or fibrous membranes (webs). To our knowledge, this is the first reported case of BCS occurring secondary to chronic kidney disease (CKD).
Anish Paudyal, Sanjay Dhungana, Sachin Bhatta, Sphurna Karki, Sapana Koirala, Parbatraj Regmi, Sagar Mani Regmi, Subhash Paudel   +7 more
wiley   +1 more source

A revised concept of moyamoya vasculopathy: developmental origins and genetic insights. [PDF]

Front Neurol
Ota T.
europepmc   +1 more source

Long‐Term Outcomes of Invasive vs Noninvasive Treatment for Intermittent Claudication: A Systematic Review and Meta‐Analysis

Cochrane Evidence Synthesis and Methods, Volume 3, Issue 6, November 2025.
In patients with leg pain from blocked arteries (intermittent claudication), this study shows that surgical procedures improve walking ability and blood flow more than exercise or medication alone but carry higher risks. The findings help guide doctors and patients in choosing the best treatment based on individual needs and risks.
Anas Elmahi, Nathalie Doolan, Mohiedin Hezima, Anwar Gowey, Daragh Moneley, Seamus McHugh, Sayed Aly, Peter Naughton, Elrasheid A. H. Kheirelseid   +8 more
wiley   +1 more source

Molecular Encoding of Ischemic Stroke and its Resolution after Human Neural Stem Cell Therapy by Extracellular Vesicles

MedComm, Volume 6, Issue 11, November 2025.
EVs can cross the blood–brain barrier and enter systemic circulation. By analyzing EV RNA cargoes before and after stroke, and following hNSC transplantation, our study shows that EV RNAs accurately reflect stroke pathology and provide insights into how hNSCs promote stroke recovery. These findings suggest that EV RNA profiles could serve as diagnostic
Chuheng Chang, Yiqing Wang, Xiaohang Liang, Renzhi Wang, Xinjie Bao   +4 more
wiley   +1 more source

A retrospective study on the predictive value of D-dimer for mortality in patients with acute arterial occlusive mesenteric ischemia. [PDF]

BMC Gastroenterol
Yang Y, Liu P, Gao R, Zhai Z, Zhou Y, Li J.   +5 more
europepmc   +1 more source

Late Onset Pulmonary Arterial Hypertension Associated With Features of Pulmonary Veno-Occlusive Disease and Rare Heterozygous Variants of <i>KDR</i> and <i>EIF2AK4</i>. [PDF]

Pulm Circ
Foris V, Brcic L, Dorfmüller P, Eichstaedt CA, Grünig E, Douschan P, John T, Zeder K, Fuchsjäger M, Kneidinger N, Kovacs G, Olschewski H.   +11 more
europepmc   +1 more source

Assessing the clinical and cost-effectiveness of endovascular vs open revascularisation in severe occlusive aorto-iliac disease (EVOCC trial): study protocol for a randomised controlled trial. [PDF]

BMJ Open
Saratzis A, Davies A, Diamantopoulos A, Davies RSM, Epstein D, Jepson M, Perez D, Apergi D, Harris KJ, Zayed H, Brookes C, Barber S, Suazo Di Paola A, Ingram L, Richardson C, Patel A.   +15 more
europepmc   +1 more source

Innovations in MRI and AI Integration for Vascular Plaque Evaluation and Overview of Deep Learning Techniques in Peripheral Vascular Disease. [PDF]

Methodist Debakey Cardiovasc J
Pomozi E, Quintero-Peña C, Csore J, Crichton A, Wang G, Karmonik C, Roy T.   +6 more
europepmc   +1 more source