Results 291 to 300 of about 38,122 (350)

Achieving robust labeling above the circle of Willis with vessel‐encoded arterial spin labeling

Magnetic Resonance in Medicine, Volume 94, Issue 4, Page 1415-1431, October 2025.
Abstract Purpose To improve the robustness of noninvasive vessel‐selective perfusion imaging and angiography using vessel‐encoded arterial spin labeling (VEASL) when applied to complex vascular geometries, such as above the circle of Willis (CoW) in the brain.
Hongwei Li, Yang Ji, He Wang, Zhensen Chen, Tiansheng Qian, Yujun Liao, Jian Wang, Joseph G. Woods, Yuriko Suzuki, Thomas W. Okell   +9 more
wiley   +1 more source

Real‐World Chemoport Outcomes in Pediatric Oncology in a Resource‐Limited Setting: A Retrospective Analysis With Pragmatic Implications

Pediatric Blood &Cancer, Volume 72, Issue 10, October 2025.
ABSTRACT Introduction Reliable long‐term venous access is crucial for pediatric oncology, particularly in resource‐limited settings where peripheral intravenous access often proves inadequate. Totally implantable venous access devices or chemoports, provide a durable and safe alternative. However, literature from newly established cancer centers in low‐
Soumitra Saha, Kumar Vineet, Raghwesh Ranjan, Parichay Singh, Rahul Sarode, Avadhesh Kumar Yadav   +5 more
wiley   +1 more source

Mycoplasma pneumoniae Infection and Progressive Cold Agglutinin Syndrome in a Child: Catastrophic Multiple Cutaneous Necrosis

Clinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT Acrocyanosis and gangrene are rare but serious manifestations of CAS caused by MP infection in children. These symptoms may lead to severe complications if not managed appropriately, highlighting the need for clinicians to remain vigilant and provide proper supportive care.
Bahareh Abtahi‐Naeini, Sharareh Babaei, Sayed Nassereddin Mostafavi, Mahsa Pourmahdi‐Boroujeni, Sara Adibfard   +4 more
wiley   +1 more source

Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy

Diabetes/Metabolism Research and Reviews, Volume 41, Issue 6, September 2025.
ABSTRACT An increasing number of individuals are at high risk of type 2 diabetes (T2DM) and its cardiovascular (CV) complications, which challenges healthcare systems with an increased risk of developing CV diseases. Patients with T2DM exhibit a unique cardiac phenotype termed diabetic cardiomyopathy (DCM).
Adam Russell‐Hallinan, Narainrit Karuna, Frank Lezoualc'h, Giuseppe Matullo, Hana Baker, Monique Bernard, Yvan Devaux, Lina Badimon, Gemma Vilahur, Jennifer Rieusset, Geneviève A. Derumeaux, Chris J. Watson   +11 more
wiley   +1 more source

Disparities in Peripheral Circulatory Complication‐Related Mortality in Type 2 Diabetes Mellitus Patients: A CDC Analysis (1999–2020)

Endocrinology, Diabetes &Metabolism, Volume 8, Issue 5, September 2025.
This national analysis reveals rising mortality from peripheral circulatory complications in U.S. type 2 diabetes patients from 1999 to 2020, with stark disparities by race, gender, and geography. American Indian/Alaska Natives, males, and rural populations were disproportionately affected, highlighting the urgent need for targeted interventions ...
Iqra Shahid, Hadia Ahmad, Saad Ashraf, Qasim Mehmood, Azka Ijaz, Suraksha Rani, Sara Sohail, Shameer Iqbal Ghuman, Mahnoor Fatima, Minaam Farooq, Hafsa Shahid, Minhal Chaudhry, Aayush Chaulagain   +12 more
wiley   +1 more source

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

Glia, Volume 73, Issue 9, Page 1817-1840, September 2025.
Main Point Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological ...
Kevin Jayaraj, Ritesh Kumar, Sukanya Shyamasundar, Thiruma V. Arumugam, Jai S. Polepalli, S. Thameem Dheen   +5 more
wiley   +1 more source

Spatiotemporal Dynamics of Central Nervous System Diseases: Advancing Translational Neuropathology via Single‐Cell and Spatial Multiomics

MedComm, Volume 6, Issue 9, September 2025.
Central nervous system (CNS) diseases are driven by spatiotemporally dynamic molecular networks. Single‐cell and spatial multiomics technologies dissect cellular heterogeneity, microenvironmental remodeling, and intercellular crosstalk. Integration of transcriptomic, epigenomic, proteomic, and metabolomic layers reveals disease‐associated regulatory ...
Mingkai Xia, Quan Liu, Wenli Zhang, Jinwen Ge, Zhigang Mei   +4 more
wiley   +1 more source

Activity and Heterogeneity of Astrocytes in Neurological Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 6, Issue 9, September 2025.
Astrocytes display heterogeneity in various neurological disorders and behavioral neuropsychiatric disorders. Astrocytes influence the progression of neurological diseases through neuroinflammation, oxidative stress, metabolic abnormalities, intercellular interactions, and a spectrum of other pathophysiological processes.
Shijie Mao, Rui Qiao, Qi Wang, Ling Shen, Daxing Li, Xinchen Huo, Jindou Wang, Kunxuan Liu, Wenjing Chen, Tianhao Zhu, Beicheng Zhang, Shuo Leng, Ying Bai   +12 more
wiley   +1 more source

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Antithrombotic Therapy in Peripheral Arterial Occlusive Disease

Chest, 1992
Abbreviations: ACD 5 absolute claudication distance; CI 5 confidence interval; INR 5 international normalized ratio; LMWH 5 low-molecular-weight heparin; MI 5 myocardial infarction; NASCET 5 North American Symptomatic Carotid Endarterectomy Trial; PGE1 5 prostaglandin E1; PGI2 5 prostaglandin I2; PTFE 5 polytetrafluoroethylene; rtPA 5 recombinant ...
G P, Clagett, R A, Graor, E W, Salzman
openaire   +5 more sources

Hyperuricemia in Patients With Peripheral Arterial Occlusive Disease

Angiology, 1974
Serum uric acid was found elevated in 25 out of 45 patients with Peripheral arterial occlusive disease. At the present time neither the precise pathogenesis of PAOD nor the exact role of SUA in vascular disorders has been determined. There exists some data suggesting on the one hand a pathogenetic role of uric acid in PAOD, probably through ADP-induced
Seitanidis, B., Balas, P., Karabelis, A., Tripolitis, A.   +3 more
openaire   +3 more sources