Results 111 to 120 of about 463,075 (306)

Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. [PDF]

, 2014
BackgroundIndividuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction.
Del Puerto, Gus, Ganz, Peter, Graf, Jonathan, Grunfeld, Carl, Hsue, Priscilla Y, Imboden, John, Nitta, Elaine, Scherzer, Rebecca, Schnell Heringer, Amanda, Shigenaga, Judy, Wu, Yuaner   +10 more
core   +2 more sources

Endothelial GPR68 Is Essential for Arteriogenesis and Represents a Therapeutic Target in a Model of Peripheral Artery Disease

Advanced Science, EarlyView.
Endothelial GPR68 is identified as a critical regulator of collateral artery growth in peripheral artery disease. Genetic and pharmacological evidence demonstrates that GPR68 integrates hemodynamic cues to drive monocyte recruitment and inflammatory remodeling, thereby promoting collateral arteriogenesis and tissue perfusion after ischemia ...
Yiyan Song, Senyi Peng, Zhilei Huang, Miao Yu, Mingyue Wu, Yuexin Zhu, Zeyi Zhou, Yongshan Liu, Yalin Zhang, Yu Huang, Zhongxing Wang, Fu‐Li Xiang, Jie Xu   +12 more
wiley   +1 more source

Prevalence and risk factors associated with peripheral artery disease in elderly patients undergoing peritoneal dialysis

Vascular Health and Risk Management, 2012
Ding-Wei Kuang,1,2,* Chiu-Leong Li,1,* Un-I Kuok,1 Kin Cheung,1 Weng-In Lio,1 Jing Xin1,21Department of Nephrology, Centro Hospitalar Conde de São Januário, Macao, China; 2Department of Nephrology, Huashan Hospital, Shanghai, China ...
Kuang DW, Li CL, Kuok UI, Cheung K, Lio WI, Xin J   +5 more
doaj  

Insulin resistance in type 1 diabetes: what is ‘double diabetes’ and what are the risks? [PDF]

, 2013
In this review, we explore the concept of ‘double diabetes’, a combination of type 1 diabetes with features of insulin resistance and type 2 diabetes.
A Caixas, AM Taylor, B Conway, B Teupe, B. M. Fisher, BF Voight, CT Prince, D Williams, D Yazici, DB Savage, DM Maahs, DM Maahs, DM Nathan, EA Nikkila, ER Christ, ES Kilpatrick, G Pambianco, G Perseghin, G Perseghin, G Roglic, G Ruotolo, H. M. Colhoun, HM Colhoun, IE Schauer, J Frystyk, J Guy, J Yip, J-L Selam, J. R. Petrie, JA Edge, JB Ferriss, JC Zgibor, JQ Purnell, JQ Purnell, JR Erbey, JR Petrie, JT Lahtela, KJ Nadeau, L Hodson, LM Thorn, M Kacerovsky, MR Taskinen, MR Taskinen, MR Taskinen, N Chaturvedi, N Sattar, N. Sattar, P Nevalainen, P Petruzzo, R Sinha, RA Heptulla, RW James, S Makimattila, S Norbert, S Vella, S. J. Cleland, SC Bain, SD Sibley, SJ Livingstone, SR Vethakkan, The Diabetes Control and Complications Trial Research Group, TJ Orchard, TJ Wilkin   +62 more
core   +3 more sources

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

Advanced Science, EarlyView.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss, Timothy Erickson, Yike Jiang, Varun Kannan, Jonathan M. Yarimi, Kristen S. Fisher, Nikita Shukla, Tim Lotze, Eyal Muscal, Kristy O. Murray   +9 more
wiley   +1 more source

Burden of peripheral artery disease and risk factors among patients with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis

BMC Endocrine Disorders
Background Diabetes is a non-communicable disease that presents a substantial public health challenge on a global scale. Peripheral artery disease is a significant macrovascular problem in diabetes mellitus characterized by atherosclerotic narrowing of ...
Kirubel Eshetu Haile, Yordanos Sisay Asgedom, Gedion Asnake Azeze, Atitegeb Alebachew Amsalu, Gizachew Ambaw Kassie, Amanuel Yosef Gebrekidan   +5 more
doaj   +1 more source

Statin use and adverse effects among adults \u3e 75 years of age: Insights from the Patient and Provider Assessment of Lipid Management (PALM) registry [PDF]

, 2018
Background: Current statin use and symptoms among older adults in routine community practice have not been well characterized since the release of the 2013 American College of Cardiology/American Heart Association guideline.
Goldberg, Anne C, Lee, L. Veronica, Louie, Michael J, Mi, Xiaojuan, Nanna, Michael G, Navar, Ann Marie, Peterson, Eric D, Robinson, Jennifer, Roger, Veronique L, Virani, Salim S, Wang, Tracy Y   +10 more
core   +2 more sources

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Diagnosis and management of peripheral artery disease in women

International Journal of Women's Health, 2012
Joy Peacock Walker, Jade S HiramotoDepartment of Surgery, University of California, San Francisco, California, USAAbstract: Peripheral artery disease (PAD) is a significant cause of morbidity and mortality in the USA.
Walker JP, Hiramoto JS
doaj  

Unusual presentation of peripheral artery disease

Ibom Medical Journal
Peripheral artery disease usually presents as intermittent claudication, with leg pain associated with walking and relieved by rest. We report a 52 year old man with pains in the left arm and peripheral vascular disease was confirmed with Doppler ...
Uwanuruochi K, Obiozoh AA
doaj   +1 more source