Results 111 to 120 of about 308,781 (312)
Advanced Science, EarlyView.This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong +6 more
wiley +1 more source
A Case With Incidental Renal Artery Stenosis and a Review of the Literature
Turkish Journal of Nephrology, 2019 Renal artery disease is frequently encountered as an incidental finding in peripheral vascular disease. In this case report, a 67- year-old lady with peripheral vascular and renal artery lesions identified at a time before they produced significant ...
Kübra KAYNAR +4 more
doaj
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 Background The relative benefit of higher statin dosing in patients with peripheral artery disease has not been reported previously. We compared the effectiveness of low‐ or moderate‐intensity (LMI) versus high‐intensity (HI) statin dose on clinical ...
T. Raymond Foley +9 more
doaj +1 more source
Advanced Science, EarlyView.The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian +9 more
wiley +1 more source
Diagnosis and management of peripheral artery disease in women
International Journal of Women's Health, 2012 Joy Peacock Walker, Jade S HiramotoDepartment of Surgery, University of California, San Francisco, California, USAAbstract: Peripheral artery disease (PAD) is a significant cause of morbidity and mortality in the USA.
Walker JP, Hiramoto JS
doaj
Unusual presentation of peripheral artery disease
Ibom Medical JournalPeripheral artery disease usually presents as intermittent claudication, with leg pain associated with walking and relieved by rest. We report a 52 year old man with pains in the left arm and peripheral vascular disease was confirmed with Doppler ...
Uwanuruochi K, Obiozoh AA
doaj +1 more source
Design and intermediate results of the Lower Extremity Arterial Disease Event Reduction (LEADER)* trial of bezafibrate in men with lower extremity arterial disease [ISRCTN4119421]. [PDF]
, 2001 BACKGROUND: Raised levels of both triglycerides and fibrinogen, each of which are reduced by bezafibrate, may contribute to lower extremity arterial disease (LEAD).
Thomas W Meade +3 more
core +1 more source
Advanced Science, EarlyView.We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du +11 more
wiley +1 more source
Microalbuminuria, peripheral artery disease, and cognitive function [PDF]
, 2008 Kidney disease may be linked to a decline in cognitive activity. We examined the association of microalbuminuria and cognitive function in a general population of older adults in the United States drawn from the National Health and Nutrition Examination ...
Shoham, D.A. +3 more
core +2 more sources
Advanced Science, EarlyView.This study introduces a foundation model‐based biomarker for risk stratification of pathological response in non‐small cell lung cancer. A Vision Mamba super‐resolution model standardizes heterogeneous CT images. A multi‐task Swin Transformer then fine‐tunes a pre‐trained lung foundation model to jointly optimize tumor segmentation and response ...
Yanglan Xu +10 more
wiley +1 more source